Hyclean Cream
Octinoxate + Oxybenzone+ Hydroquinone + Zinc oxide topical
Sun Pharmaceutical Industries Ltd.
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Indications
Hyclean Cream is used for:
Indicated for the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other undesired areas of melanin hyperpigmentation.
Adult Dose
Topical
Cream
Apply to affected areas twice daily, in the morning and before bedtime.
Child Dose
There is no recommended dosage for children under 12 years of age
Renal Dose
Administration
Contra Indications
Contraindicated in persons who have shown hypersensitivity to hydroquinone or any of the other ingredients.
Precautions
Hydroquinone may produce exogenous ochronosis, a gradual blue-black darkening of the skin. If this condition occurs, discontinue treatment. Test for skin sensitivity before using by applying a small amount to an unbroken patch of skin; check within 24 hours. Minor redness is not a contraindication, but where there is itching or vesicle formation or excessive inflammatory response, further treatment is not advised. Close patient supervision is recommended.
After clearing and during maintenance therapy, sun exposure should be avoided on bleached skin by application of a sunscreen or sunblock agent or protective clothing to prevent repigmentation. Avoid contact with eyes and mucous membranes.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Octinoxate + Oxybenzone+ Hydroquinone + Zinc oxide topical :
The following adverse reactions have been reported: dryness and fissuring of paranasal and infraorbital areas, erythema, and stinging. Occasional hypersensitivity (localized contact dermatitis) may develop.
Mechanism of Action
Topical application of hydroquinone produces a reversible depigmentation of the skin by the inhibition of the enzymatic oxidation of tyrosine to 3, 4-dihydroxyphenylalanine (DOPA) and suppression of other melanocyte metabolic processes. Exposure to sunlight or ultraviolet light will cause repigmentation of the bleached areas
Note
Hyclean Cream manufactured by Sun Pharmaceutical Industries Ltd.. Its generic name is Octinoxate + Oxybenzone+ Hydroquinone + Zinc oxide topical. Hyclean is availble in Nepal.
Farmaco Nepal drug index information on Hyclean Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.