Ibugesic Plus Tablet

Ibuprofen + Paracetamol
200mg + 325mg
Cipla Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price 1.30 NPR

Indications

Ibugesic Plus Tablet is used for: Pain and inflammation associated with musculoskeletal and joint disorders

Adult Dose

Oral Pain and inflammation associated with musculoskeletal and joint disorders Adult: (Ibuprofen 400 mg + Paracetamol 325/500 mg) 1 tab 3-4 times daily.

Child Dose

Oral Pain and inflammation associated with musculoskeletal and joint disorders Child: (Ibuprofen 100mg + Paracetamol 125mg) 1 dose tid or as required.

Renal Dose

Administration

Contra Indications

Active peptic ulcer, history of hypersensitivity to either component, recent GI bleeding, neonates.

Precautions

Bronchial asthma, renal or hepatic disorders, bleeding disorders, CV diseases, hypertension, patients on anticoagulants, aspirin/NSAIDs induced allergy, pregnancy & lactation.

Pregnancy-Lactation

Interactions

Ibuprofen antagonises the effects of furosemide & thiazides. Pethidine & propanthelene reduce absorption of paracetamol. Aspirin displaces ibuprofen from binding sites. NSAIDs blunt the effects of antihypertensives. Potentially Fatal: Increased risk of GI ulceration & bleeding with anticoagulants. Paracetamol increases the risk of liver damage in chronic alcoholics. Ibuprofen increases the risk of methotrexate toxicity & lithium toxicity.

Adverse Effects

Side effects of Ibuprofen + Paracetamol : Dyspepsia, heart burn, GI bleeding, rash, asthmatic attacks, thrombocytopenia, drug induced ulcer, drowsiness, hepatic necrosis, renal papillary necrosis, vision disturbances & disorientation; rarely nausea & vomiting can occur. Potentially Fatal: Hematemesis, agranulocytosis, severe allergic reaction.

Mechanism of Action

Ibuprofen is a potent anti-inflammatory with analgesic and antipyretic action. Its analgesic and antipyretic effects are further reinforced by paracetamol.

Note

Ibugesic Plus 200mg + 325mg Tablet manufactured by Cipla Ltd.. Its generic name is Ibuprofen + Paracetamol. Ibugesic Plus is availble in Nepal. Farmaco Nepal drug index information on Ibugesic Plus Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Ibuprofen + Paracetamol :