Junior Lanzol Tablet
Lansoprazole
15mg
Cipla Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 3.87 NPR |
Available as:
Indications
Junior Lanzol Tablet is used for:
Peptic ulcer, H.pylori infection, Gastro-oesophageal reflux disease, Hypersecretory conditions, Acid-related dyspepsia, NSAID-induced ulcers, Erosive oesophagitis
Adult Dose
Oral
Peptic ulcer
Adult: 30 mg once daily in the morning given for up to 4 wk (duodenal ulcer) or for up to 8 wk (gastric ulcer). Maintenance: 15 mg/day.
Zollinger-Ellison syndrome
Adult: Initially, 60 mg once daily in the morning and adjust as required. Daily doses >120 mg should be given in 2 divided doses.
Acid-related dyspepsia
Adult: 15-30 mg once daily in the morning for 2-4 wk.
Gastro-oesophageal reflux disease
Adult: 15-30 mg once daily in the morning for 4-8 wk. Maintenance: 15-30 mg once daily according to response.
Prophylaxis of NSAID-induced ulcers
Adult: 15-30 mg once daily in the morning.
H.pylori infection
Adult: 1-wk triple therapy: 30 mg bid combined w/ clarithromycin 500 mg bid and amoxicillin 1 g bid or combined w/ clarithromycin 250 mg bid and metronidazole 400 mg bid.
Erosive oesophagitis
Adult: 30 mg once daily in the morning for up to 8 wk, additional 8 wk if not healed. Maintenance: 15 mg once daily.
NSAID-associated ulceration
Adult: 30 mg once daily in the morning for 4-8 wk.
Elderly: No dosage adjustment needed.
Hepatic impairment: Severe: Max: 30 mg/day.
Child Dose
Oral
Gastro-oesophageal reflux disease
1-11 yr
<30 kg: 15 mg once daily in the morning for up to 12 wk;
>30 kg: 30 mg once daily in the morning for up to 12 wk. May increase doses up to 30 mg bid if patient is still symptomatic after 2 or more wk of treatment.
12-17 yr
15 mg once daily for up to 8 wk.
Erosive oesophagitis
1-11 yr
<30 kg: 15 mg once daily in the morning for up to 12 wk;
>30 kg: 30 mg once daily in the morning for up to 12 wk. May increase doses up to 30 mg bid if patient is still symptomatic after 2 or more wk of treatment.
12-17 yr 30 mg once daily for up to 8 wk.
Renal Dose
Renal impairment: No dosage adjustment needed.
Administration
Should be taken on an empty stomach. Take before meals.
Contra Indications
Hypersensitivity.
Precautions
Hepatic impairment. Gastric malignancy should be ruled out. Pregnancy and lactation.
Lactation: Not known whether distributed into breast milk; do not nurse
Pregnancy-Lactation
Interactions
Increased risk of hypomagnesaemia w/ diuretics and digoxin. May decrease plasma concentration of erlotinib, dasatinib and lapatinib. May decrease the bioavailability of itraconazole and ketoconazole. May increase plasma concentration of cilostazol and methotrexate. Reduced bioavailability w/ antacids and sucralfate.
Potentially Fatal: May decrease serum levels and pharmacological effects of rilpivirine and atazanavir.
Adverse Effects
Side effects of Lansoprazole :
1-10%
Headache (3-7%),Diarrhea (1-5%),Constipation (1-5%),Nausea (1-3%),Abdominal pain (1-3%)
<1%
Anxiety,Angina,Palpitations,Syncope,Edema,Anorexia,Dry mouth,Tenesmus,Flatulence,Melena,Myalgia,Tinnitus,Allergic reaction
Mechanism of Action
Lansoprazole is a substituted benzimidazole, and is also known as PPI due to its property to block the final step of acid secretion by inhibiting H+/K+ ATPase enzyme system in gastric parietal cell. Both basal and stimulated acid are inhibited.
Note
Junior Lanzol 15mg Tablet manufactured by Cipla Ltd.. Its generic name is Lansoprazole. Junior Lanzol is availble in Nepal.
Farmaco Nepal drug index information on Junior Lanzol Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.