Kaftus Syrup
Dextromethorphan + Chlorpheniramine + Phenylephrine
7.5mg + 2.5mg + 7.5mg
Sumy Pharmaceuticals Pvt. Ltd.
| Pack size | 50ml |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 50.00 NPR |
Available as:
Indications
Kaftus Syrup is used for:
Relief of Cough Associated with Allergies or the Common Cold
Adult Dose
Oral
Temporary Relief of Cough Associated with Allergies or the Common Cold
Syrup
30 mL [(2mg/5mg/5mg)/15mL] PO q4hr; not to exceed 180 mL/day
5 mL [(2-4mg/15mg/5-10mg)/5mL] PO q4-6hr; not to exceed 20 mL/day
Tablet
1 tab PO q4-6hr; not to exceed 6 tab/24hr
Child Dose
Oral
Temporary Relief of Cough Associated with Allergies or the Common Cold
Syrup
6-12 Years Old
2 mL [(0.75mg/2.75mg/1.75mg)/1mL] PO q4-6hr; not to exceed 12 mL/day
2 mL [(1mg/2.5-3mg/2-2.5mg)/1mL] PO q4-6hr; not to exceed 8 mL/day
1 mL [(1mg/3mg/3.5mg)/1mL] PO q4-6hr; not to exceed 6 mL/day
2.5mL [(2-4mg/15mg/5-10mg)/5mL PO q4-6hr; not to exceed 15mL/day
Tablet
1/2 tab PO q4-6hr; not to exceed 3 tabs/day
>12 Years Old
Syrup
30 mL [(2mg/5mg/5mg)/15mL] PO q4hr; not to exceed 180 mL/day
5 mL [(2-4mg/15mg/5-10mg)/5mL] PO q4-6hr; not to exceed 20 mL/day
Tablet
1 tab PO q4-6hr; not to exceed 6 tab/24hr
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Contraindicated in documented hypersensitivity; asthma attacks, narrow-angle glaucoma, symptomatic prostate hypertrophy, bladder-neck obstruction, and stenosing peptic ulcer
Precautions
Caution in elderly patients, hyperthyroidism, myocardial disease, bradycardia, partial heart block or severe arteriosclerosis when administering phenylephrine; in hypovolemia, phenylephrine use is not a substitute for replacement of blood, fluids and electrolytes, and plasma (promptly restore with loss); dilute IV and administer via large vein; extravasation precautions required
Chlorpheniramine may cause significant confusional symptoms; not for administration to premature or full-term neonates
Lactation: excretion in milk unknown/not recommended
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Dextromethorphan + Chlorpheniramine + Phenylephrine :
Hypertension,Hypotension,Palpitations,Reflex tachycardia,Severe peripheral and visceral vasoconstriction,Tachycardia,Confusion,Depression,Distress,Dizziness,Drowsiness,Excitability,Euphoria,Fatigue,Headache,Insomnia,Irritability,Restlessness,Sedation,Tremor,Anorexia,GI disturbances,Agranulocytosis,Hemolytic anemia,Thrombocytopenia,Thickening of bronchial secretions,Wheezing
Mechanism of Action
Chlorpheniramine blocks muscle responses in histamine and acts as an antagonism of the constrictor effects of histamine on respiratory smooth muscle.
Phenylephrine is a vasoconstrictor and a decongestant that relieves symptoms resulting from irritation of upper respiratory tract tissue. It shrinks swollen mucous membranes, reduces nasal congestion and tissue hyperemia.
Dextromethorphan is a cough suppressant that acts centrally on the cough center in the medulla.
Note
Kaftus 7.5mg + 2.5mg + 7.5mg Syrup manufactured by Sumy Pharmaceuticals Pvt. Ltd.. Its generic name is Dextromethorphan + Chlorpheniramine + Phenylephrine. Kaftus is availble in Nepal.
Farmaco Nepal drug index information on Kaftus Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.