Kenalog S Ointment
Gramicidin + Neomycin Sulphate + Nystatin + Triamcinolone Acetonide (Topical)
0.25mg + 2.5mg +1mg
Abbott India Ltd.
| Pack size | 3gm |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 37.77 NPR |
Indications
Kenalog S Ointment is used for:
Infected eczema, Skin infection, Corticosteriod-responsive dermatoses, Cuteneous candidiasis with superficial bacterial infection.
Adult Dose
Topical/Cutaneous
Corticosteriod-responsive dermatoses with secondary infection
Adult: As cream/ointment: Apply sparingly to the affected area 2-3 times daily.
Elderly: Use sparingly for short periods of time.
Child Dose
Topical/Cutaneous
Corticosteriod-responsive dermatoses with secondary infection
Child: As cream/ointment: Apply sparingly to the affected area 2-3 times daily.
Renal Dose
Administration
Contra Indications
Tuberculous, viral lesions of the skin (e.g. herpes simplex and varicella); fungal lesions not susceptible to nystatin, facial rosacea, acne vulgaris or perioral dermatitis. Not to be applied to the external auditory canal in patients with perforated tympanic membranes. Do not use on extensive areas to reduce risk of systemic absorption and neomycin-induced ototoxicity. Not recommended for <1 yr.
Precautions
Patients with established hearing loss. Avoid occlusive dressing and prolonged or recurrent use. Avoid contact with eyes or mucous membranes. If there is no clinical improvement after 7 days, discontinue use as the infection may be masked by the steroid. Limit use to 5 days if used on the face or on children ?1 yr. Use with caution and sparingly on inflamed or damaged skin (e.g extensive burns, trophic ulceration). Pregnancy.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Gramicidin + Neomycin Sulphate + Nystatin + Triamcinolone Acetonide (Topical) :
Prolonged use may cause sensitivity reactions, impaired wound healing, thinning of skin, striae, telangiectasia, hirsutism, hypothalamic-pituitary-adrenal axis suppression, Cushing's syndrome.
Mechanism of Action
Triamcinolone is a fluorinated corticosteroid with anti-inflammatory, antipruritic and anti-allergic actions. Nystatin, a polyene antifungal antibiotic, binds to ergosterol and interferes with the permeability of cell membrane of susceptible fungi e.g Candida spp. Neomycin is an aminoglycoside, often used topically in the infections against susceptible staphylococci and other organisms. Gramicidin, an antibacterial substance extracted from tyrothricin, is active against many Gram-positive bacteria. Used together, this combination provides a wide coverage against gram-positive, gram-negative bacteria and yeast which are responsible for most of the skin infections.
Note
Kenalog S 0.25mg + 2.5mg +1mg Ointment manufactured by Abbott India Ltd.. Its generic name is Gramicidin + Neomycin Sulphate + Nystatin + Triamcinolone Acetonide (Topical). Kenalog S is availble in Nepal.
Farmaco Nepal drug index information on Kenalog S Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.