Korandil 10 Tablet
Nicorandil
10mg
Sun Pharmaceutical Industries Ltd.
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Available as:
Indications
Korandil 10 Tablet is used for:
Angina pectoris
Adult Dose
Oral
Angina pectoris
Adult: 10 mg bid, increase if necessary. Usual dose: 10-20 mg bid. May use 5 mg bid for patients prone to headache. Max dose: 30 mg bid.
Hepatic impairment: Dose reduction may be necessary.
Child Dose
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Cardiogenic shock; hypotension; left ventricular failure with low filling pressure; lactation.
Precautions
Hypovolaemia, low systolic BP, acute pulmonary oedema, pregnancy. May impair ability to drive or operate machinery.
Pregnancy-Lactation
Interactions
Hypotensive interaction may occur with alcohol, TCAs, antihypertensives and other vasodilators.
Potentially Fatal: Enhanced hypotensive effect with sildenafil and other phosphodiesterase type-5 inhibitors.
Adverse Effects
Side effects of Nicorandil :
Headache (usually transitory), flushing, dizziness, nausea, vomiting and weakness. Hypotension and reflex tachycardia at high doses.
Mechanism of Action
Nicorandil dilates arterioles and large coronary arteries by opening the potassium channels, and stimulates guanylate cyclase causing venous vasodilatation. It therefore reduces preload and afterload, and improves coronary blood flow.
Note
Korandil 10 10mg Tablet manufactured by Sun Pharmaceutical Industries Ltd.. Its generic name is Nicorandil. Korandil 10 is availble in Nepal.
Farmaco Nepal drug index information on Korandil 10 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.