Kronofed - DS Tablet
Chlorpheniramine + Pseudoepedrine
S.R. Drug Laboratories Pvt. Ltd.
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Available as:
Indications
Kronofed - DS Tablet is used for:
Relief of Cold & Fever
Adult Dose
Relief of Cold & Flu Symptoms
Chlorpheniramine maleate 4 mg and pseudoephedrine HCl 60 mg
PO q4-6hr
Child Dose
Relief of Cold & Fever
6-12 Years Old
Chlorpheniramine maleate 2 mg and pseudoephedrine HCl 30 mg PO q4-6hr
>12 Years Old
Chlorpheniramine maleate 4 mg and pseudoephedrine HCl 60 mg PO q4-6hr
Renal Dose
Administration
Contra Indications
Contraindicated in documented hypersensitivity to the drugs or within 14 days of MAO inhibitor therapy; asthma attacks, narrow-angle glaucoma, symptomatic prostate hypertrophy, bladder-neck obstruction, and stenosing peptic ulcer
Precautions
Caution in cardiovascular disease, diabetes mellitus, prostatic hypertrophy and increased intraocular pressure when taking pseudoephedrine
Chlorpheniramine may cause significant confusional symptoms; not for administration to premature or full-term neonates
Lactation: enters breastmilk/contraindicated
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Chlorpheniramine + Pseudoepedrine :
Hypertension,Hypotension,Palpitations,Reflex tachycardia,Severe peripheral and visceral vasoconstriction,Tachycardia,Confusion,Depression,Distress,Dizziness,Excitability,Euphoria,Fatigue,Headache,Insomnia,Irritability,Restlessness,Sedation,Tremor,Anorexia,Agranulocytosis,Hemolytic anemia,Thrombocytopenia,Thickening of bronchial secretions,Wheezing
Mechanism of Action
Chlorpheniramine blocks muscle responses in histamine and acts as an antagonism of the constrictor effects of histamine on respiratory smooth muscle.
Pseudoephedrine stimulates the alpha-adrenergic receptors causing bronchodilation and vasoconstriction.
Note
Kronofed - DS Tablet manufactured by S.R. Drug Laboratories Pvt. Ltd.. Its generic name is Chlorpheniramine + Pseudoepedrine. Kronofed - DS is availble in Nepal.
Farmaco Nepal drug index information on Kronofed - DS Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.