L-Ret Cream

Clotrimazole 1% Topical
1% w/w
Deurali Janta Pharmaceuticals Pvt. Ltd.
Pack size 15gm
Dispensing mode
Source
Agent
Retail Price 55.00 NPR

Indications

L-Ret Cream is used for: Skin and nail fungal infections, Tinea pedis, Tinea cruris, Tinea corporis, Candidiasis, Pityriasis versicolor

Adult Dose

Topical/Cutaneous Skin and nail fungal infections: Adult: Apply 2 or 3 times daily. Onychomycosis: for 6 months. Tinea pedis & Dermatomycoses: for 4 weeks.

Child Dose

Tinea Corporis/Tinea Pedis Apply to affected area q12hr for 4 weeks Tinea Cruris >2 years: Apply to affected area q12hr for 2 weeks Candidiasis Gently massage sufficient clotrimazole into affected and surrounding area q12hr; reconsider diagnosis if no improvement after 4 weeks Tinea Versicolor Gently massage sufficient clotrimazole into affected and surrounding area q12hr; reconsider diagnosis if no improvement after 4 weeks

Renal Dose

Administration

Contra Indications

Hypersensitivity.

Precautions

Avoid contact with eyes upon topical application. Childn <3 yrs. Pregnancy, lactation.If local intolerance develops, consider withdrawal of the medicine and institution of appropriate therapy. Lactation: Excretion in milk unknown; use with caution

Pregnancy-Lactation

Pregnancy category B during 2nd and 3rd trimester; safety in 1st trimester not established

Interactions

Antagonism with polyene antibiotics.

Adverse Effects

Side effects of Clotrimazole 1% Topical : Elevated serum AST (SGOT) concentrations (15%) Topical: Erythema, stinging, irritation; hypersensitivity reactions; contact dermatitis. Edema, Pruritus, Burning, Stinging, Peeling, Urticaria, Skin fissures

Mechanism of Action

Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.

Note

L-Ret 1% w/w Cream manufactured by Deurali Janta Pharmaceuticals Pvt. Ltd.. Its generic name is Clotrimazole 1% Topical. L-Ret is availble in Nepal. Farmaco Nepal drug index information on L-Ret Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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