Larinate Injection
Artesunate
60mg
Ipca Laboratories Ltd.
| Pack size | 5ml |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 371.20 NPR |
Indications
Larinate Injection is used for:
Malaria, Schistosomiasis
Adult Dose
Falciparum malaria especially in quinidine-resistant patients
Adult: PO: 4 mg/kg once daily x3 days (with mefloquine)
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Hepatic or renal insufficiency. Pregnancy and lactation.
Lactation: unknown
Pregnancy-Lactation
Interactions
Antimalarial potentiating action seen with mefloquine, primaquine and tetracycline. Additive effect with chloroquine. Antagonistic effect with pyrimethamine and sulphonamides.
Adverse Effects
Side effects of Artesunate :
Generally well-tolerated, Cardiotoxicity (high doses), Neurotoxicity observed in animal studies, Drug induced fever, Skin rash
Mechanism of Action
Artesunate is a potent and rapidly-acting blood schizontocide derived from the leaves of the chinese herb, Armesia annua. The exact mode of action is not clear but clinical studies have confirmed the effectiveness of artesunate in P. vivax and falciparum malaria. Unclear, may inhibit DNA replication & transcription.
Note
Larinate 60mg Injection manufactured by Ipca Laboratories Ltd.. Its generic name is Artesunate. Larinate is availble in Nepal.
Farmaco Nepal drug index information on Larinate Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.