Available as:
Indications
Levolin 2 Tablet is used for:
Asthma, Chronic obstructive pulmonary disease (COPD)
Adult Dose
Oral
Adults: 1-2 mg, three times daily.
Inhaler: 1-2 puffs as required
Nebuliser Solutions
Adults: The recommended starting dosage is 0.63 mg administered three to four times a day, every 6 to 8 hours, by nebulization.
Patients 12 years of age and older with more severe asthma or patients who do not respond adequately to a dose of 0.63 mg of Levosalbutamol Nebuliser Solution, may benefit from a dosage of 1.25 mg three times a day.
Levosalbutamol Nebuliser Solution is supplied in unit-dose ampoules and requires no dilution before administration by nebulization.
Child Dose
Oral
Children above 12 years: 1-2 mg, three times daily.
Children (6 -11 years): 5 ml (1 mg), three times daily.
Children (2 -5 years): Up to 0.1 mg/kg body weight (not more than 1 mg) three times daily.
Inhaler: 1-2 puffs as required
Nebuliser Solutions
Child above 12 years old: The recommended starting dosage is 0.63 mg administered three to four times a day, every 6 to 8 hours, by nebulization.
Patients 12 years of age and older with more severe asthma or patients who do not respond adequately to a dose of 0.63 mg of Levosalbutamol Nebuliser Solution, may benefit from a dosage of 1.25 mg three times a day.
Children (6 months-11 years): The recommended dosage is 0.31 mg administered three times a day, by nebulization.
Routine dosing should not exceed 0.63 mg three times a day.
Levosalbutamol Nebuliser Solution is supplied in unit-dose ampoules and requires no dilution before administration by nebulization.
Renal Dose
Administration
Contra Indications
Levosalbutamol is contraindicated in patients with a history of hypersensitivity to Levosalbutamol or any of its components.
Precautions
Particular caution is advised in acute severe asthma as this effect may be potentiated by hypoxia and by concomitant treatment with xanthine derivatives, steroids and diuretics. Serum potassium levels should be monitored in such situations.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Levosalbutamol :
Hypocalcaemia, palpitation, fine tremors of the skeletal muscle and muscle cramps may occur. The other likely side effects are nausea, vomiting, burning substernal or epigastric pain and diarrhoea.
Mechanism of Action
Levosalbutamol is a single isomer beta-2 agonist that differs from racemic salbutamol by elimination of (S)-salbutamol. Levosalbutamol is an effective bronchodilator whose primary mechanism of action is unimpeded by (S)-salbutamol.Thus, when compared with racemic salbutamol, clinically comparable bronchodilation can be achieved with doses that substantially lessen beta-mediated side effects. Levosalbutamol produces bronchodilatation through stimulation of beta-2-adrenergic receptors in bronchial smooth muscles, thereby causing relaxation of bronchial muscle fibres.
Note
Levolin 2 2mg Tablet manufactured by Cipla Ltd.. Its generic name is Levosalbutamol. Levolin 2 is availble in Nepal.
Farmaco Nepal drug index information on Levolin 2 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.