Lopam Tablet
Hyoscine Butylbromide
10mg
Genetica Laboratory Pvt. LTd.
| Pack size | 100's |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 15.00 NPR |
Available as:
Indications
Lopam Tablet is used for:
Gastrointestinal tract spasm, Abdominal pain, Genitourinary spasm
Adult Dose
Oral
Gastrointestinal tract spasm; Genitourinary spasm
Adult: 20 mg 4 times daily.
Parenteral
Gastrointestinal tract spasm; Genitourinary spasm
Adult: 20 mg IM/IV repeated after 30 min if needed.
Max Dosage: 100 mg daily.
Child Dose
Oral
Gastrointestinal tract spasm; Genitourinary spasm
Child: 6-12 yr: 10 mg tid.
Renal Dose
Administration
Contra Indications
Narrow-angle glaucoma, acute haemorrhage, paralytic ileus, tachycardia due to cardiac insufficiency, myasthenia gravis.
Precautions
Hepatic/renal disease, pyloric stenosis, urinary retention, prostatic hyperplasia, psychosis, seizure disorders, ulcerative colitis, coronary artery disease, tachyarrhythmias, heart failure, hypertension. Elderly, children, pregnancy, lactation.
Pregnancy-Lactation
Interactions
Additive sedative effects with alcohol or other CNS depressants. Reduced effects with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine, tacrine).
Potentially Fatal: Effect potentiated by other anticholinergic drugs and TCAs.
Adverse Effects
Side effects of Hyoscine Butylbromide :
Flushing, postural hypotension, tachycardia, fibrillation. Rarely psychotic reactions. Dizziness, drowsiness, fatigue, headache, memory loss. Dry skin, erythema, increased sensitivity to light, rash. Bloatedness, constipation, dry throat, dysphagia, nausea, vomiting, xerostomia. Dysuria, urinary retention. Tremor, weakness. Impaired accommodation, blurred vision, cycloplegia, dryness, narrow-angle glaucoma, increased intraocular pain, itching, photophobia, pupil dilation. Dry nose. Decreased diaphoresis, heat intolerance. Ophthalmic: Somnolence, dermatitis, oedema, exudate, follicular conjunctivitis, increased IOP, local irritation, photophobia, vascular and respiratory congestion.
Potentially Fatal: CNS depression, coma, circulatory and respiratory failure.
Mechanism of Action
Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.
Note
Lopam 10mg Tablet manufactured by Genetica Laboratory Pvt. LTd.. Its generic name is Hyoscine Butylbromide. Lopam is availble in Nepal.
Farmaco Nepal drug index information on Lopam Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.