Lotensyl AT 10/50 Tablet
Lercanidipine + Atenolol
10mg + 50mg
Sun Pharmaceutical Industries Ltd.
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Indications
Lotensyl AT 10/50 Tablet is used for:
Hypertension
Adult Dose
Oral
Hypertension
Adult: 1-2 tab once daily, titrate dose based on patient response.
Child Dose
Renal Dose
Administration
Tablet is to be taken empty stomach.
Contra Indications
Known history of allergy.
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Lercanidipine + Atenolol :
Common
Sleepiness
Headache
Ankle swelling
Flushing (sense of warmth in the face, ears, neck and trunk)
Slow heart rate
Tiredness
Palpitations
Nausea
Edema (swelling)
Constipation
Cold extremities
Mechanism of Action
Lercanidipine is a dihydropyridine calcium channel blocker. It inhibits influx of Ca into cardiac and smooth muscle, causing relaxation of vascular smooth muscle thus reducing peripheral vascular resistance and BP.
Atenolol selectively and competitively blocks β1-adrenergic receptors but has little or no effect on β2-receptors except at high doses. It has negative inotropic effects without intrinsic sympathomimetic and membrane-stabilising activities.
Note
Lotensyl AT 10/50 10mg + 50mg Tablet manufactured by Sun Pharmaceutical Industries Ltd.. Its generic name is Lercanidipine + Atenolol. Lotensyl AT 10/50 is availble in Nepal.
Farmaco Nepal drug index information on Lotensyl AT 10/50 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.