M Chlor Tablet
Chlorpheniramine Maleate
4mg
Manoj
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Indications
M Chlor Tablet is used for:
Urticaria, Sneezing, Watery eyes, Allergic conditions, Anaphylactic shock, Rhinitis, Itching
Adult Dose
Oral
Adult: 4 mg every 4-6 hr. Max: 24 mg daily.
Parenteral
Adjunct in the emergency treatment of anaphylactic shock
Adult: 10-20 mg IM, SC, or slow IV inj over 1 min. Max dose: 40 mg daily.
Child Dose
Oral
Child: 1-2 yr: 1 mg bid,
2-5 yr: 1 mg every 4-6 hr,
6-12 yr: 2 mg every 4-6 hr.
Max: 6 mg daily (1-5 yr); 12 mg daily (6-12 yr).
Parenteral
Adjunct in the emergency treatment of anaphylactic shock
Child: 87.5 mcg/kg SC 4 times daily
Renal Dose
Administration
Contra Indications
Hypersensitivity, Neonates.
Precautions
Elderly, pylori duodenal obstruction, angle-closure glaucoma, urinary retention, prostatic hyperplasia, epilepsy, renal and hepatic impairment. May affect performance of skilled tasks. BPH, bladder neck obstruction, hypertension. Pregnancy, lactation.
Pregnancy-Lactation
Interactions
Potentiates sedative effect of psychotropic drugs e.g. barbiturates, hypnotics, opioid analgesics, anxiolytics and antipsychotics. Interaction with alcohol could be dangerous (sedation/excitation).
Adverse Effects
Side effects of Chlorpheniramine Maleate :
CNS depression, sedation, drowsiness, lassitude, dizziness. GI upsets, anorexia, or increased appetite, epigastric pain, blurring of vision, dysuria, dryness of mouth, tightness in chest, hypotension, muscular weakness, tinnitus, euphoria, headache, paradoxical CNS stimulation.
Potentially Fatal: CV collapse and respiratory failure.
Mechanism of Action
Chlorphenamine is an H1-receptor antagonist which competetively blocks H1-receptor sites on tissues.
Note
M Chlor 4mg Tablet manufactured by Manoj. Its generic name is Chlorpheniramine Maleate. M Chlor is availble in Nepal.
Farmaco Nepal drug index information on M Chlor Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.