Magnesium Injection

Magnesium Sulphate inj
2ml
Hindusthan Pharmaceuticals Ltd.
Pack size 1's
Dispensing mode
Source
Agent
Retail Price 15.44 NPR

Indications

Magnesium Injection is used for: Eclampsia, Cerebral palsy, Hypomagnesemia, Torsades de pointes, Barium poisoning

Adult Dose

Adult: IV Hypomagnesaemia Symptomatic deficiency: 1-2 g over 5-60 mins, then maintain at 0.5-1 g/hr if needed. Severe: 1-2 g/hr for 3-6 hr, then 0.5-1 g/hr as needed to correct deficiency. Torsades de pointes W/ pulses: Loading dose: 1-2 g over 5-60 mins, then maintain at 0.5-1 g/hr as needed. Pulseless: 1-2 g over 5-20 mins. Barium poisoning 1-2 g. Cerebral oedema 2.5 g. Eclampsia Loading dose: 4-5 g over 10-15 mins, followed by either a continuous infusion of 1 g/hr or deep IM doses of 4-5 g into alternate buttocks 4 hrly. If seizure recurs, an additional IV dose of 2-4 g may be given. Not to exceed 30-40 g/24 hr. IM Hypomagnesaemia Mild deficiency: 1 g 6 hrly for 4 doses. Severe deficiency: Up to 250 mg/kg w/in 4 hr.

Child Dose

Renal Dose

Administration

Contra Indications

Parenteral: Heart block, severe renal impairment, myocardial damage.

Precautions

Renal impairment, myasthaenia gravis, digitalised patients; pregnancy. Monitor serum-magnesium concentrations.

Pregnancy-Lactation

Interactions

Enhances neuromuscular blockers, digitalis glycosides.

Adverse Effects

Side effects of Magnesium Sulphate inj : Hypermagnesaemia characterised by nausea, vomiting, flushing, thirst, hypotension, drowsiness, confusion, slurred speech, double vision, bradycardia, muscle weakness. Hypocalcaemia; paralytic ileus.

Mechanism of Action

Magnesium sulfate decreases levels of acetylcholine in motor nerve terminals. It also acts on the myocardium by decreasing the rate of SA node impulse formation and prolonging the conduction time.

Note

Magnesium 2ml Injection manufactured by Hindusthan Pharmaceuticals Ltd.. Its generic name is Magnesium Sulphate inj. Magnesium is availble in Nepal. Farmaco Nepal drug index information on Magnesium Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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