Methergin Injection

Methyl Ergometrine Maleate
0.2mg
Novartis India Ltd.
Pack size 1ml
Dispensing mode
Source
Agent
Retail Price 24.08 NPR

Available as:

Indications

Methergin Injection is used for: Migraine, Miscarriage, Uterine hemorrhage, Spontaneous or elective abortion, Uterine atony, Second stage of labor

Adult Dose

Oral: Prophylaxis of postpartum haemorrhage Adult: 200 mcg 3-4 times daily in the puerperium for 2-7 days. Intramuscular Treatment and prophylaxis of postpartum and postabortal haemorrhage Adult: 200 mcg. May repeat every 2-4 hr. Max: 5 doses. Intravenous Treatment and prophylaxis of postpartum and postabortal haemorrhage Adult: As an emergency measure: 200 mcg by slow inj over at least 1 minute, may repeat every 2-4 hr, up to a max of 5 doses.

Child Dose

Renal Dose

Administration

Contra Indications

Hypertension, eclamptic or previously hypertensive patients, heart disease, venoatrial shunts, mitral valve stenosis, obliterative vascular disease. Do not use in cases of threatened spontaneous abortion. Pregnancy.

Precautions

Captivation of the placenta may occur if given during the 2nd or 3rd stage of labour prior to delivery of the placenta; use in this situation should only be done by a qualified personnel. Avoid prolonged use. Caution in patients with sepsis, hepatic or renal impairment. Lactation.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Methyl Ergometrine Maleate : Headache, dizziness, hallucinations; tinnitus; nausea, vomiting, foul taste, diarrhoea; hypertension, temporary chest pain, palpitations, bradycardia; nasal congestion, dyspnoea; diaphoresis; thrombophlebitis; haematuria; water intoxication; leg cramps; allergic reactions. Potentially Fatal: Shock.

Mechanism of Action

Ergometrine causes contraction of the uterine muscle. At low doses, there is an increase in frequency and amplitude of contractions while at higher doses, the basal tone of the uterus is increased. Ergometrine also causes vasoconstriction of peripheral and cerebral vessels.

Note

Methergin 0.2mg Injection manufactured by Novartis India Ltd.. Its generic name is Methyl Ergometrine Maleate. Methergin is availble in Nepal. Farmaco Nepal drug index information on Methergin Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Methyl Ergometrine Maleate :