Monte DT 4 Tablet
Montelukast
4mg
Alive Pharmaceutical. Pvt. Ltd.
| Pack size | 50's |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 7.00 NPR |
Available as:
Indications
Monte DT 4 Tablet is used for:
Asthma, Allergic rhinitis
Adult Dose
Oral
Chronic asthma
Adult: As film-coated tab: 10 mg once daily in the evening.
Allergic rhinitis
Adult: 10 mg once daily.
Prophylaxis of exercise-induced asthma
Adult: 10 mg at least 2 hr prior to exercise; do not take additional doses w/in 24 hr.
Elderly: No dosage adjustment needed.
Hepatic impairment: Mild to moderate: No dosage adjustment needed.
Child Dose
Asthma
Prophylaxis and maintenance treatment in patients aged >12 months
<12 months: Safety and efficacy not established
12-24 months: 4 mg (granules) PO once daily in evening
2-6 years: 4 mg (chewable tablet or granules) PO once daily in evening
6-15 years: 5 mg (chewable tablet) PO once daily in evening
>15 years: 10 mg (conventional tablet) PO once daily in evening
Exercise-Induced Bronchospasm
Prophylaxis
6-15 years: 5 mg (chewable tablet) PO 2 hours before exercise; do not take additional dose within 24 hours
>15 years: 10 mg PO 2 hours before exercise; do not take additional dose within 24 hours
If taking drug for another indication, do not take additional dose to prevent EIB
Perennial Allergic Rhinitis
<6 months: Safety and efficacy not established
6-24 months: 4 mg (granules) PO once daily
2-6 years: 4 mg (chewable tablet or granules) PO once daily
6-15 years: 5 mg (chewable tablet) PO once daily
>15 years: 10 mg (conventional tablet) PO once daily
Seasonal Allergic Rhinitis
<2 years: Safety and efficacy not established
2-6 years: 5 mg (chewable tablet) or 4 mg (granules) PO once daily
6-15 years: 5 mg (chewable tablet) PO once daily
>15 years: 10 mg (conventional tablet) PO once daily
Renal Dose
Renal impairment: No dosage adjustment needed.
Administration
Contra Indications
Hypersensitivity.
Precautions
Not for the relief of acute bronchospasm. Not to be used as monotherapy for the prevention of exercise-induced bronchospasm. Patients in whom asthma is precipitated by aspirin or other NSAIDs should continue to avoid aspirin and NSAIDs. Do not abruptly substitute for oral or inhaled corticosteroids. Be alert for any signs of Churg-Strauss syndrome. Pregnancy and lactation. Children <6 mth.
Lactation: Unknown whether agent is excreted in breast milk, use with caution
Pregnancy-Lactation
Interactions
Induced hepatic metabolism resulting to decreased plasma concentration w/ potent inducers of cytochrome P450 isoenzymes (e.g. phenobarbital, phenytoin, rifampicin).
Adverse Effects
Side effects of Montelukast :
>10%
Headache (18.4%; similar to placebo)
1-10%
>2%
Abdominal pain,Eczema,Influenza,Laryngitis,Pharyngitis,Viral infection,Wheezing,Dental pain,Dizziness,Dyspepsia, Dental pain (2%),Dizziness (2%),Dyspepsia (2%)Elevated liver function tests (2%),Fever (2%),Gastroenteritis (2%),Nasal congestion (2%),Otitis (2%),Rash (2%),Urticaria (2%),
>1%
Bronchitis,Cough,Sinusitis,Upper respiratory tract infection
<1%
Allergic granulomatous angiitis (Churg-Strauss syndrome; rare),Cholestatic hepatitis (rare),Aggressive behavior, altered behavior, suicidal thoughts
Potentially Fatal: Anaphylaxis, Churg-Strauss syndrome.
Mechanism of Action
Montelukast is a selective leukotriene receptor antagonist that blocks the effects of cysteinyl leukotrienes in the airways.
Note
Monte DT 4 4mg Tablet manufactured by Alive Pharmaceutical. Pvt. Ltd.. Its generic name is Montelukast. Monte DT 4 is availble in Nepal.
Farmaco Nepal drug index information on Monte DT 4 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.