NARIZ Tablet

Cinnarizine
25MG
Nepal Pharmaceuticals Pvt. Ltd.
Pack size 14's
Dispensing mode
Source
Agent
Retail Price 3.25 NPR

Indications

NARIZ Tablet is used for: Nausea and vomiting, motion sickness, vertigo, meniere's disease, peripheral vascular diseases, cerebrovascular disorders, vestibular disorders

Adult Dose

Oral Peripheral vascular disease Adult: 75 mg bid or tid. Motion sickness Adult: 30 mg 2 hr before travel then 15 mg 8 hrly during the journey if necessary. Cerebrovascular disorders Adult: 75 mg once daily. Vertigo and vestibular disorders Adult: 30 mg tid or 75 mg 1-2 times daily.

Child Dose

Oral Motion sickness Child: 5-12 yr 15 mg 2 hr before travel then 7.5 mg 8 hrly during the journey as necessary. Vertigo and vestibular disorders Child: 5-12 yr 15 mg tid.

Renal Dose

Administration

Should be taken with food.

Contra Indications

Proven hypersensitivity to the drug. Parkinson's disease. Childn and neonates.

Precautions

Hypotension; pregnancy; lactation; elderly. May impair ability to drive or operate machineries.

Pregnancy-Lactation

Interactions

CNS depressant effect enhanced with alcohol. Action potentiated by domperidone. Increased sedative effect w/ CNS depressants or TCAs.

Adverse Effects

Side effects of Cinnarizine : Extrapyramidal symptoms sometimes associated with severe depression. Drowsiness, headache, GI upsets, unsteadiness, headache; rarely skin and hypersensitivity reactions, dry mouth, blurred vision, urinary difficulty or retention, constipation and increased gastric reflux, fatigue. Hypolipidaemic effect.

Mechanism of Action

Cinnarizine has calcium-channel blocking activity selective for arterial smooth muscle. It also has some antihistamine activity. Cinnarizine acts as a labyrinthine sedative. It also improves microcirculation by reducing ischaemia-induced blood viscosity.

Note

NARIZ 25MG Tablet manufactured by Nepal Pharmaceuticals Pvt. Ltd.. Its generic name is Cinnarizine. NARIZ is availble in Nepal. Farmaco Nepal drug index information on NARIZ Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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