Nebasulf Skin Ointment Ointment

Bacitracin + Neomycin Sulphate + Sulphacetamide

Pfizer Ltd.

Pack size
Dispensing mode
Source
Agent
Retail Price	59.20 NPR

Indications

Nebasulf Skin Ointment Ointment is used for: Bacterial skin infections

Adult Dose

Adult: Topical: Cream/Ointment: Apply 3 times/day.

Child Dose

Renal Dose

Administration

Contra Indications

Hypersensitivity to aminoglycosides. Pre-existing nerve deafness. Neonates and infants <2 yr.

Precautions

Avoid application in large quantities and prolonged use. Pregnancy and lactation. Liver and renal impairment. Avoid contact with eyes or mucous membranes

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Bacitracin + Neomycin Sulphate + Sulphacetamide : >10% Allergic contact dermatitis (60%) 1-10% Erythema Itching Edema Local irritation Stinging Burning

Mechanism of Action

Neomycin, an aminoglyoside with antimicrobial spectrum similar to gentamicin, binds to the 30S subunits of the bacterial ribosome, inhibiting protein synthesis and thereby disrupting DNA synthesis. It is active against many gram-negative aerobes and against some strains of staphylococci. Bacitracin, on the other hand, inhibits bacterial cell wall synthesis and is active against many gram-positive bacteria (e.g. staphylococci, streptococci, corynebacteria and clostridia) and some gram-negative species (e.g. Neisseria and Haemophilus influenzae). They are often found in combinations in topical preparations as broad spectrum antibacterial agents. sulfacetamide: Para-aminobenzoic acid (PABA) inhibitor; restricts folic acid synthesis required for bacterial growth

Note

Nebasulf Skin Ointment Ointment manufactured by Pfizer Ltd.. Its generic name is Bacitracin + Neomycin Sulphate + Sulphacetamide. Nebasulf Skin Ointment is availble in Nepal. Farmaco Nepal drug index information on Nebasulf Skin Ointment Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.