Neurogen Tablet
Hydroxocobalamin
0.5mg
Florid Laboratories Pvt. Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 8.00 NPR |
Available as:
Indications
Neurogen Tablet is used for:
Vitamin B12 deficiency, Cyanide poisoning
Adult Dose
Adult
Intramuscular
30 mcg daily for 5 to 10 days followed by 100 to 200 mcg monthly.
Child Dose
Children
Intramuscular
1 to 5 mg over a period of 2 or more weeks in doses of 100 mcg, then 30 to 50 mcg every 4 weeks for maintenance.
Renal Dose
Administration
Contra Indications
Hypersensitivity to any component of this medication.
Precautions
The validity of diagnostic vitamin B12 or folic acid blood assays could be compromised by medications, and this should be considered before relying on such tests for therapy.
Vitamin B12 is not a substitute for folic acid and since it might improve folic acid deficient megaloblastic anemia, indiscriminate use of vitamin B12 could mask the true diagnosis.
Hypokalemia and thrombocytosis could occur upon conversion of severe megaloblastic to normal erythropoiesis with B12 therapy. Therefore, serum potassium levels and the platelet count should be monitored carefully during therapy.
Vitamin B12 deficiency may suppress the signs of polycythemia vera. Treatment with vitamin B12 may unmask this condition.
Pregnancy-Lactation
Interactions
history of interaction with ARI Sodium Iodide (I123) 1-12 MBq (sodium iodide i-123)
ARI Sodium Iodide (I123) 100-750 MBq (sodium iodide i-123)
arsenic trioxide
Chloracol (chloramphenicol)
chloramphenicol
Chloromycetin (chloramphenicol)
Chloromycetin Sodium Succinate (chloramphenicol)
Hicon (sodium iodide-i-131)
Iodotope (sodium iodide-i-131)
sodium iodide i-123
sodium iodide-i-131
Trisenox (arsenic trioxide)
Adverse Effects
Side effects of Hydroxocobalamin :
Mild transient diarrhea, itching, transitory exanthema, feeling of swelling of entire body, and anaphylaxis.
A few patients may experience pain after injection of hydroxocobalamin.
Mechanism of Action
Vitamin B12 with hydroxyl group complexed to cobalt which can be displaced by cyanide resulting in cyanocobalamin that is renally excreted.
Note
Neurogen 0.5mg Tablet manufactured by Florid Laboratories Pvt. Ltd.. Its generic name is Hydroxocobalamin. Neurogen is availble in Nepal.
Farmaco Nepal drug index information on Neurogen Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.