Normal Saline Infusion

Sodium Chloride 0.9%
Venus
Pack size 1
Dispensing mode
Source
Agent
Retail Price 25.00 NPR

Indications

Normal Saline Infusion is used for: Dehydration, Excessive sweating, Water and electrolyte imbalance, Metabolic alkalosis, Diluting or dissolving drugs, Intra-ocular or topical irrigation during surgical procedure, dry nasal membranes including dry nose resulting from cold and allergy medications.

Adult Dose

Adult: IV Replacement of fluid and electrolytes As 0.9% soln: Dosage depends on age, wt, clinical condition and laboratory determinations of the patient. Hypernatraemia As 0.9% soln: Dosage depends on age, wt, clinical condition and laboratory determinations of the patient. Irrigation Irrigation of the bladder, eye, general skin and wound cleansing As 0.9% soln: Use as directed. Eye drop: 1 drop in the affected eye (s) every 3 or 4 hours or as directed by a physician. Nasal drop: Nasal congestion As 0.9% soln: Infants, children & adults : 2-6 drops into each nostril as needed daily.

Child Dose

Child IV Replacement of fluid and electrolytes As 0.9% soln: Dosage depends on age, wt, clinical condition and laboratory determinations of the patient. Hypernatraemia As 0.9% soln: Dosage depends on age, wt, clinical condition and laboratory determinations of the patient. Irrigation Irrigation of the bladder, eye, general skin and wound cleansing As 0.9% soln: Use as directed. Eye drop: 1 drop in the affected eye (s) every 3 or 4 hours or as directed by a physician. Nasal drop: Nasal congestion As 0.9% soln: Infants, children & adults : 2-6 drops into each nostril as needed daily.

Renal Dose

Administration

Contra Indications

Conditions whereby admin of sodium chloride would be detrimental. Not to be used to induce emesis. Sustained release tablets: GI disorders associated with strictures or diverticula.

Precautions

Hypertension, heart failure, peripheral or pulmonary oedema, impaired renal function, liver cirrhosis, preeclampsia. Maintain adequate water intake. Pregnancy. Inj of 3 or 5% sodium chloride solution should be given via a large vein at a rate not exceeding 100 ml/hr. Monitor fluid balance, serum electrolytes and acid base balance espcially during prolonged treatment. Caution when used in patients who are receiving corticosteroids or corticotropin.

Pregnancy-Lactation

Interactions

May affect serum concentrations of lithium.

Adverse Effects

Side effects of Sodium Chloride 0.9% : Hypernatraemia; thirst, reduced salivation and lachrymation, fever, tachycardia, hypertension, headache, dizziness, restlessness, irritability and weakness. Burning or irritation of the eye may occur temporarily when first applied. Other side effects are redness, pain, swelling in or around the eyes, sensitivity to light, and headache. Potentially Fatal: Intra-amniotic inj of hypertonic solutions: Disseminated intravascular coagulation, renal necrosis, cervical and uterine lesions, pulmonary embolism, pneumonia and death.

Mechanism of Action

Sodium chloride is the major extracellular cation. It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes. It is also used as diluents for infusion of compatible drug additives.

Note

Normal Saline Infusion manufactured by Venus. Its generic name is Sodium Chloride 0.9%. Normal Saline is availble in Nepal. Farmaco Nepal drug index information on Normal Saline Infusion is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Sodium Chloride 0.9% :