Normogel Chewable Tabet

Aluminium Hydroxide + Magnesium Hydroxide
Deurali Janta Pharmaceuticals Pvt. Ltd.
Pack size
Dispensing mode
Source
Agent
Retail Price

Available as:

Indications

Normogel Chewable Tabet is used for: Heartburn, Reflux oesophagitis, Hyperacidity, Peptic ulcer, Constipation, Indigestion

Adult Dose

Adult: PO Gastric Hyperacidity, Heartburn: Up to 1 g/day. Hyperphosphataemia in chronic renal failure Up to 10 g/day in divided doses w/ meals. 10-20 mL PO between meals & qHS

Child Dose

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity to aluminium salts.

Precautions

Chronic renal impairment; CHF; oedema; cirrhosis and low Na diets; patients with recent GI haemorrhage. Administer 2-3 hrs before/after another medication to minimise drug interactions. Pregnancy and lactation. Lactation: excretion in milk unknown; use caution

Pregnancy-Lactation

Interactions

Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine. Magnesium Hydroxide: Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.

Adverse Effects

Side effects of Aluminium Hydroxide + Magnesium Hydroxide : >10% Aluminum oxide,Chalky taste,Constipation,Fecal impaction,Stomach cramps Frequency Not Defined Aluminum oxide,Nausea,Vomiting,Aluminum intoxication,Hypophosphatemia,Osteomalacia,Magnesium oxide,Diarrhea,Hypermagnesemia

Mechanism of Action

Alumunium hydroxide acts on the HCl in the stomach by neutralization, forming aluminium chloride salt and water. Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.

Note

Normogel Chewable Tabet manufactured by Deurali Janta Pharmaceuticals Pvt. Ltd.. Its generic name is Aluminium Hydroxide + Magnesium Hydroxide. Normogel is availble in Nepal. Farmaco Nepal drug index information on Normogel Chewable Tabet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Aluminium Hydroxide + Magnesium Hydroxide :