Nucarnit Tablet
Levocarnitine
330MG
Emcure Pharmaceuticals Ltd.
| Pack size | 10's |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 26.57 NPR |
Indications
Nucarnit Tablet is used for:
Congestive heart failure, Diabetic nephropathy, Intermittent claudication, Kidney disease, Chronic Fatigue Syndrome, Heart Diseases, High Cholesterol, Dementia and Memory impairment, Down Syndrome, Male infertility
Adult Dose
Adults: Tablet: 330 mg two or three times daily.
Child Dose
Infants and children: 50 to 100 mg/kg/day in divided doses, with a maximum of 3 g/day. Dosage should begin at 50 mg/kg/day.
The exact dosage will depend on clinical response.
Renal Dose
Administration
Consume oral solution slowly, may be mixed with drinks and space doses evenly throughout the day (q3-4hr) preferably during or after meals (may decrease GI distress)
Contra Indications
Hypersensitivity.
Precautions
Gastrointestinal reactions may result from a too rapid consumption of Levocarnitine.
The safety and efficacy of oral levocarnitine has not been evaluated in patients with renal insufficiency. Chronic administration of high doses of oral levocarnitine in patients with severely compromised renal function or in ESRD patients on dialysis may result in accumulation of the potentially toxic metabolites, trimethylamine (TMA) and trimethylamine-N-oxide (TMAO), since these metabolites are normally excreted in the urine
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Levocarnitine :
Generally Levocarnitine is well tolerated. However, few side effects including transient nausea and vomiting, abdominal cramps, and diarrhoea may occur
Mechanism of Action
Quaternary ammonium compound found in all mammalian tissue (particularly striated muscle).
Important for lipid catabolism; essential for FFA transport from cytosol to mitochondria where they are oxidized.
Note
Nucarnit 330MG Tablet manufactured by Emcure Pharmaceuticals Ltd.. Its generic name is Levocarnitine. Nucarnit is availble in Nepal.
Farmaco Nepal drug index information on Nucarnit Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.