Ocudor Eye Drops

Dorzolamide 2% eye prep
5ML
FDC Pharmaceutical Pvt. Ltd.
Pack size
Dispensing mode
Source
Agent
Retail Price 483.84 NPR

Indications

Ocudor Eye Drops is used for: Ocular hypertension; Open-angle glaucoma

Adult Dose

Ophthalmic Ocular hypertension; Open-angle glaucoma Adult: Instill 1 drop tid;

Child Dose

Ophthalmic Ocular hypertension; Open-angle glaucoma Child: Instill 1 drop tid;

Renal Dose

Administration

Contra Indications

Hypersensitivity Severe reanl impairment (CrCl<30 mL/min)

Precautions

Patient w/ history of renal calculi, pre-existing chronic corneal defects and/or history of intra-ocular surgery. Hepatic and severe renal (CrCl <30 mL/min) impairment. Pregnancy and lactation. Patient Counselling This drug may cause dizziness and visual disturbances, if affected do not drive and operate machinery. Monitoring Parameters Monitor intraocular pressure periodically. Lactation: Not known whether distributed into breast milk; Do not nurse

Pregnancy-Lactation

Interactions

May increase the serum concentration of alpha-/beta-agonists (indirect-acting). May enhance the adverse/toxic effects of other carbonic anhydrase inhibitors.

Adverse Effects

Side effects of Dorzolamide 2% eye prep : Ocular burning, stinging and discomfort; superficial punctate keratitis, ocular allergic reactions (e.g. conjunctivitis, itching, lid reactions), blurred vision, redness, tearing, dryness, photophobia, transient myopia, eyelid crusting, palpebral reactions, ocular pain, irreversible corneal decompensation, ocular hypotony; acidosis, electrolyte imbalance, systemic allergic reactions (e.g. angioedema, pruritus, bronchospasm, urticaria), dizziness, paraesthesia, throat irritation, dyspnoea, contact dermatitis, bitter taste, headache, nausea, asthenia/fatigue, urolithiasis. Rarely, iridocyclitis. Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anaemia, and other blood dyscrasias.

Mechanism of Action

Dorzolamide reversibly inhibits carbonic anhydrase resulting in reduction of hydrogen ion secretion at renal tubule and increased renal excretion of Na, K, bicarbonate, and water, thus decreasing the production of aqueous humor. It also inhibits carbonic anhydrase in CNS to retard abnormal and excessive discharge from CNS neurons.

Note

Ocudor 5ML Eye Drops manufactured by FDC Pharmaceutical Pvt. Ltd.. Its generic name is Dorzolamide 2% eye prep. Ocudor is availble in Nepal. Farmaco Nepal drug index information on Ocudor Eye Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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