Ocurest Eye Drops
Naphazoline + Phenylephrine eye prep
(0.05%)+(0.12%)
Centaur Pharmaceuticals Pvt. Ltd.
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| Retail Price | 106.34 NPR |
Indications
Ocurest Eye Drops is used for:
For temporary relief of burning & irritation caused by dust, smoke, sun glare, swimming, TV, contact lenses, cold & superficial inflammatory or allergic eye conditions.
Adult Dose
Ophthalmic
Instill 1-2 drops into affected eye(s) bid or tid.
Child Dose
Child: >12
Ophthalmic
Instill 1-2 drops into affected eye(s) bid or tid.
Renal Dose
Administration
Contra Indications
Ophth: Narrow-angle glaucoma, corneal damage, acute iritis and other serious eye disease.
Precautions
Patient w/ CV disease, HTN, DM, hyperthyroidism, local infection or injury. Childn. Pregnancy and lactation. Patient Counselling This drug may cause drowsiness, temporary blurred vision, and transient mydriasis, if affected, do not drive or operate machinery. Remove contact lenses prior to ophth admin and reinsert after 10-15 min.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Naphazoline + Phenylephrine eye prep :
Significant: Rebound vasodilation or congestion (prolonged/frequent use). Nervous: Nervousness, headache, drowsiness, dizziness, weakness.
GI: Nausea. CV: Cardiac irregularities, HTN. Resp: Burning, stinging, sneezing, increased discharge (nasal).
Endocrine:Hyperglycaemia.
Ophthalmologic: Mydriasis, ocular hyperaemia, increased redness, irritation, discomfort, blurred vision, punctuate keratitis, lacrimation, increased intraocular pressure. Dermatologic: Sweating.
Ophthalmic solutions may liberate pigment granules from the iris, corneal clouding/damage.
Mechanism of Action
Naphazoline is an alpha adrenergic receptor agonist which causes vasoconstriction by stimulating arterioles of the conjunctiva and nasal mucosa thus reducing swelling, redness and discomfort when applied to mucous membranes.
Phenylephrine causes vasoconstriction of the arterioles of the nasal mucosa and conjunctiva; activates the dilator muscle of the pupil to cause contraction; produces vasoconstriction of arterioles in the body and produces systemic arterial vasoconstriction.
Note
Ocurest (0.05%)+(0.12%) Eye Drops manufactured by Centaur Pharmaceuticals Pvt. Ltd.. Its generic name is Naphazoline + Phenylephrine eye prep. Ocurest is availble in Nepal.
Farmaco Nepal drug index information on Ocurest Eye Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.