Orecure Ear Drop
Chloramphenicol + Prednisolone ear prep
Vilco Laboratories Pvt Ltd
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Indications
Orecure Ear Drop is used for:
Inflammatory conditions of ear including bacterial infections.
Adult Dose
Aural
Adult: 1-2 drops 4-6 hrly
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensensitivity
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Chloramphenicol + Prednisolone ear prep :
Ear drops: Ototoxicity.
Mechanism of Action
Chloramphenicol inhibits bacterial protein synthesis by binding to 50s subunit of the bacterial ribosome, thus preventing peptide bond formation by peptidyl transferase. It has both bacteriostatic and bactericidal action against H. influenzae, N. meningitidis and S. pneumoniae.
Prednisolone decreases inflammation by inhibition of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It suppresses the immune system by reducing the activity and production of the lymphocytes and eosinophils.
Note
Orecure Ear Drop manufactured by Vilco Laboratories Pvt Ltd. Its generic name is Chloramphenicol + Prednisolone ear prep. Orecure is availble in Nepal.
Farmaco Nepal drug index information on Orecure Ear Drop is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.