Peptica Gel Gel
Aluminium Oxide + Magnesium Hydroxide + Simethicon
Geno Pharmaceuticals Ltd.
Pack size | 200ml |
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Dispensing mode | |
Source | |
Agent | |
Retail Price | 55.58 NPR |
Indications
Peptica Gel Gel is used for:
Hyperacidity, Gastric ulcer duodenal ulcer and gastritis
Adult Dose
Chew1-2 tablets or 2-4 tsf after meals and at bedtime as needed (up to 4 times a day).
Child Dose
Renal Dose
Administration
After meals and at bedtime as needed. For best results, drink a half glass of water or other liquid after each dose.
Contra Indications
Hypophosphataemia. Simethicon is contrindicated in renal failure, severely debiliated patients, 1st trimester of pregnancy.
Precautions
Renal dysfunction, low phosphate diet, prolonged use.
Pregnancy-Lactation
Interactions
Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine.
Magnesium Hydroxide: Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.
Simethicon: None well documented.
Adverse Effects
Side effects of Aluminium Oxide + Magnesium Hydroxide + Simethicon :
Diarrhoea, constipation, nausea, vomiting.
Mechanism of Action
Aluminum hydroxide: Neutralizes stomach hydrocloride to form AlCl3 salt plus water; increases gastric pH.
Magnesium hydroxide: Promotes bowel evacuation by causing osmotic retention of fluid, which causes the colon to distend with increased peristaltic activity; forms magnesium chloride when reacts with hydrochloric acid.
Simethicone: Disperses and prevents gas pockets in the GI system by decreasing surface tension of gas bubles.
Note
Peptica Gel Gel manufactured by Geno Pharmaceuticals Ltd.. Its generic name is Aluminium Oxide + Magnesium Hydroxide + Simethicon. Peptica Gel is availble in Nepal.
Farmaco Nepal drug index information on Peptica Gel Gel is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.