Pirocin Ointment
Mupirocin 2% Topical
2%
Universal Formulation
| Pack size | 5 gm |
|---|---|
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Indications
Pirocin Ointment is used for:
Impetigo, Folliculitis, Secondary skin infections
Adult Dose
Topical/Cutaneous
Impetigo
Adult: As 2% oint: Apply to affected area tid for 5-10 days; re-evaluate after 3-5 days if no clinical response.
Secondary skin infections
Adult: As 2% cream: Apply to affected area tid for up to 10 days; re-evaluate after 3-5 days if no clinical response.
Child Dose
Topical/Cutaneous
Impetigo
Child: >2 mth Apply to affected area tid for 5-10 days; re-evaluate after 3-5 days if no clinical response.
Secondary skin infections
Child: >3 mth Apply to affected area tid for up to 10 days; re-evaluate after 3-5 days if no clinical response.
Renal Dose
Administration
Contra Indications
This drug is contraindicated in individuals with a history of sensitivity reactions to Mupirocin or any of the components of the preparation.
Precautions
Patient w/ extensive burns and wounds. Renal impairment. Childn. Pregnancy and lactation. Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi
Lactation: Not known if distributed into milk; recommended that nursing be temporarily discontinued during therapy
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Mupirocin 2% Topical :
Burning, stinging, pruritus, pain, rash, erythema, dry skin, tenderness, cellulitis, pain or bleeding secondary to eczema, secondary wound infection, urticaria, swelling, increased exudates, contact dermatitis, furunculosis, exfoliative dermatitis.
Rarely, systemic reactions (e.g. nausea, headache, dizziness, abdominal pain, ulcerative stomatitis, systemic allergic reactions).
Mechanism of Action
Mupirocin inhibits protein synthesis of the bacteria by binding to isoleucyl transfer RNA-synthetase. It is active against gram-positive and some gram-negative bacteria.
Note
Pirocin 2% Ointment manufactured by Universal Formulation. Its generic name is Mupirocin 2% Topical. Pirocin is availble in Nepal.
Farmaco Nepal drug index information on Pirocin Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.