Rhinex Tablet
Acetaminophen (paracetamol) + Phenylephrine
Simca
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 3.00 NPR |
Indications
Rhinex Tablet is used for:
Relief of Mild to Moderate Pain & Congestion, Flu Symptoms, Common Cold
Adult Dose
Relief of Mild to Moderate Pain & Congestion, Flu Symptoms, Common Cold
650 mg/10 mg PO q4hr PRN; not to exceed 6 doses/24hr
1000 mg/10 mg PO q6hr PRN; not to exceet 4 doses/24hr
Child Dose
Relief of Mild to Moderate Pain & Congestion, Flu Symptoms, Common Cold
<12 years: Ask a pediatrician
>12 years
650mg/10mg PO q4hr PRN; not to exceed 6 doses/24hr
1000mg/10mg PO q6hr PRN; not to exceet 4 doses/24hr
Renal Dose
Administration
Contra Indications
Both drugs contraindicated in documented hypersensitivity to either drug or components; known G-6-PD deficiency
Precautions
Caution in elderly patients, hyperthyroidism, myocardial disease, bradycardia, partial heart block or severe arteriosclerosis when administering phenylephrine; in hypovolemia, phenylephrine use is not a substitute for replacement of blood, fluids and electrolytes, and plasma (promptly restore with loss); dilute IV and administer via large vein; extravasation precautions required
Acetaminophen hepatotoxicity possible in chronic alcoholics following various dose levels; severe or recurrent pain or high or continued fever may indicate a serious illness; contained in many OTC products and combined use with these products may result in toxicity due to cumulative doses exceeding recommended maximum dose
Acetaminophen: Risk for rare, but serious skin reactions that can be fatal; these reactions include Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP); symptoms may include skin redness, blisters and rash
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Acetaminophen (paracetamol) + Phenylephrine :
Hypertension
Reflex tachycardia
Severe peripheral and visceral vasoconstriction
Dizziness
Excitability
Headache
Restlessness
Tremor
Dermatologic rash
Anemia blood dyscrasias (neutropenia, pancytopenia, leukopenia)
Bilirubin and alkaline phosphatase
Mechanism of Action
Acetaminophen blocks pain impulse generation peripherally and may inhibit the generation of prostaglandin in the CNS. Reduces fever by inhibiting the hypothalamic heat-regulating center.
Phenylephrine is a vasoconstrictor and a decongestant that relieves symptoms resulting from irritation of upper respiratory tract tissue. It shrinks swollen mucous membranes, reduces nasal congestion and tissue hyperemia.
Note
Rhinex Tablet manufactured by Simca. Its generic name is Acetaminophen (paracetamol) + Phenylephrine. Rhinex is availble in Nepal.
Farmaco Nepal drug index information on Rhinex Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.