Roxibest 150 Tablet

Roxithromycin
150mg
Blue Cross Laboratories Pvt. Ltd.
Pack size 1
Dispensing mode
Source
Agent
Retail Price

Indications

Roxibest 150 Tablet is used for: Pneumonia, Pharyngitis, Susceptible infections, Sinusitis, Otitis media, Cellulitis,Tonsillitis, Folliculitis, Carbuncles, Prostatitis, Urethritis, Acute and chronic bronchitis, Bronchopneumonia, Furuncles, Pyoderma, Impetigo and infected dermatitis, Cervicitis and salpingitis

Adult Dose

Oral Susceptible infections Adult: 150 mg bid or 300 mg once daily for 5-10 days in susceptible infections. Hepatic impairment: Usual daily doses should be halved in hepatic impairment.

Child Dose

Oral Susceptible infections Child: 6-40 kg: 5-8 mg/kg daily.

Renal Dose

Renal impairment: Dosage adjustment may be required.

Administration

Should be taken on an empty stomach. Take at least 15 min before meals.

Contra Indications

Hypersensitivity. Porphyria.

Precautions

Hepatic impairment. Monitor liver function. Prolonged treatment increases risk of hepatotoxicity. History of arrhythmias.

Pregnancy-Lactation

Interactions

May raise serum levels of ciclosporin and digoxin. Increased risk of rhabdomyolysis when used with simvastatin.

Adverse Effects

Side effects of Roxithromycin : Nausea, vomiting, abdominal pain, diarrhoea, weakness, malaise, anorexia, constipation, dyspepsia, flatulence; hepatitis; rashes, headache, dizziness, weakness, changes in blood counts; increased liver enzyme values; eosinophilia; rarely, acute pancreatitis.

Mechanism of Action

Roxithromycin inhibits protein synthesis by irreversibly binding to the 50s ribosomal subunits thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth.

Note

Roxibest 150 150mg Tablet manufactured by Blue Cross Laboratories Pvt. Ltd.. Its generic name is Roxithromycin. Roxibest 150 is availble in Nepal. Farmaco Nepal drug index information on Roxibest 150 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Roxithromycin :