Saclo Tablet

Aceclofenac
100mg
THE MADRAS PHARMACEUTICALS
Pack size
Dispensing mode
Source
Agent
Retail Price 6.50 NPR

Indications

Saclo Tablet is used for: Rheumatoid arthritis, Osteoarthritis, Ankylosing spondylitis;

Adult Dose

Adult: PO Ankylosing spondylitis; Osteoarthritis; Rheumatoid arthritis 100 mg twice daily. SR Tablet : The recommended dose is 200 mg, once daily. Injection The recommended dose is 150 mg once or twice daily for 5 days or as recommended by the physician. Gel: Topical gel used thinly twice daily or as directedby the physician. Hepatic Impairment Reduce initial dose to 100 mg daily .

Child Dose

Renal Dose

Administration

Should be taken with food. Take w/ or immediately after meals.

Contra Indications

Hypersensitivity to aspirin or NSAIDs; moderate to severe renal impairment; pregnancy (3rd trimester); history of peptic ulceration or GI bleed; patients with infections.

Precautions

Cautiously administer to patients with GI disease, ulcerative colitis, Crohn's disease, haematological abnormalities, hepatic porphyria; history of bronchial asthma; history of heart failure or hypertension; mild renal, hepatic or cardiac impairment. May impair ability to drive or operate machinery. Elderly.

Pregnancy-Lactation

Interactions

May increase plasma concentrations of lithium and digoxin. Increased nephrotoxicity when used with diuretics or ciclosporin. Monitor serum potassium when used with potassium-sparing diuretics and ACE inhibitors. May enhance activity of anticoagulants. May increase risk of methotrexate toxicity when administered within 24 hr of methotrexate admin. Increased risk of GI bleed with other NSAIDs. Increased risk of convulsion with quinolones.

Adverse Effects

Side effects of Aceclofenac : Diarrhoea, nausea, dyspepsia, abdominal pain, dizziness, rashes; increased LFTs. Potentially Fatal: Severe GI bleeding; nephrotoxicity; blood dyscrasias.

Mechanism of Action

Aceclofenac, a phenylacetic acid derivative, has antiinflammatory and analgesic properties. It is a potent inhibitor of cyclo-oxygenase which is involved in the production of prostaglandins.

Note

Saclo 100mg Tablet manufactured by THE MADRAS PHARMACEUTICALS. Its generic name is Aceclofenac. Saclo is availble in Nepal. Farmaco Nepal drug index information on Saclo Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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