Serobid R Capsule

Salmeterol
50mcg
Cipla Ltd.
Pack size 1's
Dispensing mode
Source
Agent
Retail Price 175.68 NPR

Indications

Serobid R Capsule is used for: Chronic asthma, COPD

Adult Dose

Inhalation Asthma Prevention and Maintenance, COPD Maintenance Adult: As inhaler: 2 puffs (50 mcg) twice daily; up to 100 mcg twice daily if needed. Prevention of Exercise-Induced Asthma 2 puffs (50 mcg) at least 30 min prior to exercise.

Child Dose

Inhalation Child > 4 years Asthma Prevention and Maintenance, COPD Maintenance As inhaler: 2 puffs (50 mcg) twice daily; up to 100 mcg twice daily if needed. Prevention of Exercise-Induced Asthma 2 puffs (50 mcg) at least 30 min prior to exercise.

Renal Dose

Administration

Contra Indications

Contraindicated in patients with hypersensitivity to Salmeterol or to the any excipient of this preparation. Monotherapy in the treatment of asthma. Treatment of status asthmaticus, other acute episodes of asthma or COPD.

Precautions

Patient w/ CV disease, CNS disorders, DM, hyperthyroidism, hypokalaemia, seizure disorders, ketoacidosis. Not intended for the relief of acute bronchospasm. Hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor pulmonary function, BP, heart rate, CNS stimulation, hepatic function; glucose and K levels..

Pregnancy-Lactation

Interactions

Diuretics, corticosteroids and xanthines may augment hypokalaemia. Risk of severe hypertension when used with MAOIs, TCAs and other sympathomimetics. Increased susceptibility to cardiac arrhythmias caused by digoxin and other cardiac glycosides.

Adverse Effects

Side effects of Salmeterol : >10% Headache (13-17%),Pain (1-12%) 1-10% Nasal congestion (9%),Hypertension (4%),Edema (1-3%),Dizziness (4%),Sleep disturbance (1-3%),Migraine (1-3%),Contact dermatitis (1-3%),Urticaria (3%),Hyperglycemia (1-3%),Articular rheumatism (1-3%),Paresthesia (1-3%),Muscular stiffness (1-3%),Photodermatitis (1-2%),Bronchitis (7%),Influenza (5%),Rigidity (1-3%),Rhinitis (5%),Asthma (3%) Frequency Not Defined Conjunctivitis,Hyperglycemia,Keratitis,Oral candidiasis,Chest tightness,Cataracts,Hypokalemia,Myositis

Mechanism of Action

Salmeterol is a direct-acting sympathomimetic which relaxes bronchial smooth muscle by its selective action on beta 2 receptors with little effect on heart rate.

Note

Serobid 50mcg R Capsule manufactured by Cipla Ltd.. Its generic name is Salmeterol. Serobid is availble in Nepal. Farmaco Nepal drug index information on Serobid R Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Salmeterol :