Slimage Tablet
Orlistat
120mg
Deurali Janta Pharmaceuticals Pvt. Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 60.00 NPR |
Indications
Slimage Tablet is used for:
Obesity
Adult Dose
Oral
Obesity
Adult:
Indicated in patients with pretreatment BMI >30 kg/m², or BMI >27 kg/m² in presence of other risk factors or diseases (eg, HTN, DM, hyperlipidemia)
120 mg tid w/ each main meal.
Patients w/ BMI >28 kg/m2 irrespective of any risk factors: 60 mg tid.
Omit dose if a meal is missed or contains no fat. Discontinue if patient is unable to lose at least 5% of the body wt during the 1st 12 wk of therapy.
Child Dose
<12 years: Safety and efficacy not established
Renal Dose
Administration
Should be taken with food. Take immediately before or during or up to 1 hr after each main meal. If a meal is missed or contains no fat, the dose may be omitted.
Contra Indications
Chronic malabsorption syndrome. Cholestasis. Lactation
Precautions
Patient w/ history of hyperoxaluria or Ca oxalate nephrolithiasis. Monitoring Parameters Monitor BMI, diet, LFT, serum glucose (in patient w/ DM), thryroid function (in patient w/ thyroid disease).
Lactation: Not recommended; not known if orlistat is distributed in breast milk
Pregnancy-Lactation
Interactions
May decrease absorption of oral fat-soluble vitamins, amiodarone, propafenone. May decrease plasma levels of ciclosporin. May alter the effects of warfarin (monitor INR). May elevate plasma levels of pravastatin.
Adverse Effects
Side effects of Orlistat :
1-10%
Oily spotting (5%)
Frequency Not Defined
Faecal urgency and incontinence, flatulence, fatty stools or discharge, increased defecation; headache, anxiety, fatigue, menstrual irregularities; abdominal pain/discomfort.
Potentially Fatal: Anaphylaxis; angioedema.
Mechanism of Action
Orlistat is a reversible gastric and pancreatic lipase inhibitor. It exerts antiobesity effects by limiting the absorption of dietary fats through inhibition of triglyceride hydrolysis. It does not exert appetite suppressant effects.
Note
Slimage 120mg Tablet manufactured by Deurali Janta Pharmaceuticals Pvt. Ltd.. Its generic name is Orlistat. Slimage is availble in Nepal.
Farmaco Nepal drug index information on Slimage Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.