Sonaderm Cream

Clobetasol + Miconazole + Neomycin Topical
10GM
Blue Cross Laboratories Pvt. Ltd.
Pack size 1's
Dispensing mode
Source
Agent
Retail Price 59.20 NPR

Indications

Sonaderm Cream is used for: Corticosteriod-responsive dermatoses w/ secondary infection by bacteria & fungus.

Adult Dose

Topical/Cutaneous Corticosteriod-responsive dermatoses w/ secondary infection Adult: Cream/Oint: Apply gently to the affected area 2-3 times daily.

Child Dose

Topical/Cutaneous Severe inflammatory skin disorders Child: >2 yr: As cream/ointment. Apply a thin layer onto the affected area(s) 1-2 times daily until improvement occurs. Not to be used for >7 days without medical supervision.

Renal Dose

Administration

Contra Indications

Hypersensitivity. Childn <12 yrs. Long-term treatment of ulcerative conditions, rosacea, pruritus; presence of acute infections.

Precautions

Glaucoma; hypothyroidism; hepatic failure, renal impairment; psychoses; childn and elderly. Should not enter eyes. Long-term continuous topical therapy should be avoided where possible, particularly in infants and children, as adrenal suppression can occur readily even without occlusion. If used in childhood, or on the face, courses should be limited to 5 days and occlusion should not be used. If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye. If used in psoriasis careful patient supervision is important.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Clobetasol + Miconazole + Neomycin Topical : Perioral dermatitis, striae esp in flexures. Dermal and epidermal atrophy esp on the face, steroid purpura, erythema, pruritus, photosensitivity, irritation, burning, contact dermatitis.

Mechanism of Action

Clobetasol is a very potent corticosteroid used in short-term treatment of various inflammatory skin conditions. Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients. Neomycin is an aminoglycoside antibiotic that binds to ribosomal 30S and 50S subunits of susceptible bacteria, thus inhibiting protein synthesis; it also causes misreading of the genetic codes on the mRNA template.

Note

Sonaderm 10GM Cream manufactured by Blue Cross Laboratories Pvt. Ltd.. Its generic name is Clobetasol + Miconazole + Neomycin Topical. Sonaderm is availble in Nepal. Farmaco Nepal drug index information on Sonaderm Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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