Spanil Tablet
Hyoscine Hydro Bromide
10mg
Beximco Pharmaceuticals Ltd.
| Pack size | 10's |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 3.00 NPR |
Indications
Spanil Tablet is used for:
Motion sickness
Adult Dose
Adult: Motion sickness As hydrobromide: 300 mcg 30 mins before journey, then 300 mcg 6 hrly if needed.
Max: 3 doses in 24 hr.
Child Dose
Children over 12 years: Motion sickness As hydrobromide: 300 mcg 30 mins before journey, then 300 mcg 6 hrly if needed.
Max: 3 doses in 24 hr.
Children 4-12 years: 1 tablet 30 mins before journey. Maximum 2 tablet in 24 hours.
Chidren 3-4 years: 1/2 tab 30 mins before journey. Maximum 1 tablet in 24 hours.
Renal Dose
Administration
Contra Indications
Narrow-angle glaucoma, acute haemorrhage, paralytic ileus, tachycardia due to cardiac insufficiency, myasthenia gravis.
Precautions
Hepatic/renal disease, pyloric stenosis, urinary retention, prostatic hyperplasia, psychosis, seizure disorders, ulcerative colitis, coronary artery disease, tachyarrhythmias, heart failure, hypertension. Elderly, children, pregnancy, lactation
Pregnancy-Lactation
Interactions
Additive sedative effects with alcohol or other CNS depressants. Reduced effects with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine, tacrine).
Potentially Fatal: Effect potentiated by other anticholinergic drugs and TCAs.
Adverse Effects
Side effects of Hyoscine Hydro Bromide :
Flushing, postural hypotension, tachycardia, fibrillation. Rarely psychotic reactions. Dizziness, drowsiness, fatigue, headache, memory loss. Dry skin, erythema, increased sensitivity to light, rash. Bloatedness, constipation, dry throat, dysphagia, nausea, vomiting, xerostomia. Dysuria, urinary retention. Tremor, weakness. Impaired accommodation, blurred vision, cycloplegia, dryness, narrow-angle glaucoma, increased intraocular pain, itching, photophobia, pupil dilation. Dry nose. Decreased diaphoresis, heat intolerance. Ophthalmic: Somnolence, dermatitis, oedema, exudate, follicular conjunctivitis, increased IOP, local irritation, photophobia, vascular and respiratory congestion.
Potentially Fatal: CNS depression, coma, circulatory and respiratory failure.
Mechanism of Action
Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.
Note
Spanil 10mg Tablet manufactured by Beximco Pharmaceuticals Ltd.. Its generic name is Hyoscine Hydro Bromide. Spanil is availble in Nepal.
Farmaco Nepal drug index information on Spanil Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.