Stemiz 10 Tablet

Astemizole
10mg
Zydus Pharmaceuticals
Pack size 1
Dispensing mode
Source
Agent
Retail Price 3.42 NPR

Indications

Stemiz 10 Tablet is used for: Allergic conditions.

Adult Dose

Oral Allergic conditions Adult: 10 mg once daily.

Child Dose

Oral Allergic conditions Child: 6-12 yr: 5 mg once daily.

Renal Dose

Administration

Should be taken on an empty stomach.

Contra Indications

Hypersensitivity. Porphyria.

Precautions

Prostatic hypertrophy, urinary retention, glaucoma, pyloroduodenal obstruction, epilepsy; children and elderly. Avoid in patients with cardiac disease, significant hepatic disease, known or suspected prolongation of the QT interval, hypokalaemia and other electrolyte imbalances. Not to exceed recommended doses due to risk of arrhythmias.

Pregnancy-Lactation

Interactions

Imidazole, triazole antifungals, and the macrolide antibacterials inhibit the hepatic metabolism of astemizole. Avoid concomitant admin of other potentially arrhythmogenic drugs. Co-admin with diuretics may cause electrolyte imbalance. Concurrent use with terfenadine is not recommended.

Adverse Effects

Side effects of Astemizole : Increased appetite, wt gain. Rashes, hypersensitivity reactions. CNS depression eg, drowsiness, headache, psychomotor impairments; urinary retention, dry mouth, blurred vision, GI disturbances. Potentially Fatal: Ventricular arrhythmias, including torsades de pointes.

Mechanism of Action

Astemizole is a piperidine derivative, non-sedating antihistamine.

Note

Stemiz 10 10mg Tablet manufactured by Zydus Pharmaceuticals. Its generic name is Astemizole. Stemiz 10 is availble in Nepal. Farmaco Nepal drug index information on Stemiz 10 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Astemizole :