Suminat Tablet
Sumatriptan
25mg
Sun Pharmaceutical Industries Ltd.
| Pack size | 1 |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 54.13 NPR |
Available as:
Indications
Suminat Tablet is used for:
Migraine, Cluster headache
Adult Dose
Oral
Migraine
Adult: >18 yr: 50-100 mg repeated at 2-hr intervals if migraine recurs. Max: 200 mg/24 hr.
Mild to moderate hepatic impairment: Max single dose: 50 mg.
Severe hepatic impairment: Contraindicated
Child Dose
<18 years: Safety and efficacy not established
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Not to be used prophylactically and in patients with basilar or hemiplegic or ophthalmoplegic migraine. History of MI or stroke, severe hepatic impairment, ischaemic heart disease, uncontrolled hypertension, peripheral vascular disease, hypersensitivity to sulfonamides.
Precautions
Conditions predisposing to seizures, presence of coronary risk factors, cardiac arrhythmias, renal or hepatic impairment, elderly, pregnancy, lactation.
Lactation: Excreted in breast milk at very low levels; minimize infant to potential exposure by avoiding breastfeeding for 8-12 hours after administration
Pregnancy-Lactation
Interactions
Concurrent use increased risk of vasospastic reaction with ergotamine and related compounds.
Potentially Fatal: Increased risk of serotonin syndrome with concurrent use of SSRI, MAOIs or within 14 days of stopping MAOIs. Admin of ergotamine or related compounds within the previous 24 hr.
Adverse Effects
Side effects of Sumatriptan :
>10%
Injection site reaction (<86%),Paresthesia (5-14%),Dizziness (12%),Warm/hot sensation (11%)
1-10%
Chest discomfort/pressure/tightness (2-5%),Jaw or neck tightness (1-5%),Diaphoresis (2%),Burning sensation (7%),Cold sensation (1%),Dysphagia,Sore throat (3%),Malaise (1%),Abdominal distress (1%)
Frequency Not Defined
Agitation,Cardiac arrhythmia: V-fib/V-tach (rare),Dysuria,Eye irritation,Flushing,MI and coronary artery vasospasm in patients with CAD risk factors (extremely rare),Nasal discomfort,Palpitations,Tingling,Weakness
Potentially Fatal: Cardiac arrhythmias, MI.
Mechanism of Action
Sumatriptan is a selective serotonin agonist that acts at 5-HT1 receptors. It causes vasoconstriction of cranial arteries and/or inhibition of neurogenic inflammatory processes in the CNS. A small but significant delay in gastric emptying also occurs.
Note
Suminat 25mg Tablet manufactured by Sun Pharmaceutical Industries Ltd.. Its generic name is Sumatriptan. Suminat is availble in Nepal.
Farmaco Nepal drug index information on Suminat Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.