Synolizer Syrup

DIsodium Hydrogen Citrate
Siddhartha Pharmaceuticals Pvt. Ltd.
Pack size 100ml
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Indications

Synolizer Syrup is used for: Used for the treatment of Urinary tract infection, Kidney stones, Uremic acidosis, Burning micturition, Acidosis following diarrhoea, Renal tubular acidosis

Adult Dose

Adults : 15 ml to 30 ml two to three times per day, after dissolving in water

Child Dose

Children above 13 years : 15 ml to 30 ml two to three times per day, after dissolving in water Children from 7 years to 12 years: 5 ml three times per day Infants & children up to 7 years: 2 ml three times per day

Renal Dose

Administration

Should be taken with food. Take plenty of water and juices with the medicine.

Contra Indications

Contraindicated in patients with sodium-restricted diets, with severe renal impairment, or known hypersensitivity to any of the ingredients.

Precautions

Patients should be directed to dilute adequately with water and preferably, to take each dose after meals to avoid saline laxative effect. Sodium salts should be used cautiously in patients with cardiac failure, hypertension, impaired renal function, peripheral and pulmonary edema, and toxemia of pregnancy. Periodic examinations and determinations of serum electrolytes, particularly serum bicarbonate level, should be carried out in those patients with renal disease in order to avoid these complications. Hypoventilatory states hypocalcemia, alkalosis, renal disease, neonates, hypertension, heart failure, odema, electrolytes imbalance.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of DIsodium Hydrogen Citrate : Nausea, vomiting, diarrhea, and stomach pain may occur. Cramping in stomach,Flatulence,Diuresis (Excess production of urine),Anxiety,Gastrointestinal ulceration,Diarrhea,Deficiency of potassium in blood,Tiredness,Mood swings

Mechanism of Action

Sodium citrate is absorbed and metabolized to sodium bicarbonate, thus acting as a systemic alkalizer. The effects are essentially those of chlorides before absorption and those of bicarbonates subsequently. Oxidation is virtually complete so that less than 5% of sodium citrate is excreted in the urine unchanged. Disodium Hydrogen Citrate works by neutralizing the excess acid in the blood and urine.It is also used as acidity regulator and sequestrat.

Note

Synolizer Syrup manufactured by Siddhartha Pharmaceuticals Pvt. Ltd.. Its generic name is DIsodium Hydrogen Citrate. Synolizer is availble in Nepal. Farmaco Nepal drug index information on Synolizer Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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