T Zine Tablet
Cetirizine
10mg
Quest Pharmaceuticals Pvt. Ltd.
| Pack size | 15's |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 3.00 NPR |
Indications
T Zine Tablet is used for:
Allergic rhinitis, Hay fever, Allergies, Urticaria
Adult Dose
Oral
Allergic conditions
Adult: 10 mg once daily or 5 mg bid.
Elderly: Initially, 5 mg once daily.
Hepatic impairment: Initially, 5 mg once daily.
Syrup:
Adults: 2 teaspoon once daily or 1 teaspoon twice daily.
Child Dose
Oral
Allergic conditions
Child: 6-23 mth 2.5 mg once daily increased to max of 2.5 mg bid in childn >12 mth; 2-5 yr 5 mg once daily or in 2 divided doses; >6 yr 10 mg once daily or in 2 divided doses.
Syrup:
Children over 6 years: 2 teaspoon once daily or 1 teaspoon twice daily.
Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoon twice daily.
<2 years: Safety and efficacy not established
Renal Dose
Renal impairment
GFR >50 mL/min: Dose adjustment not necessary
GFR ? 50 mL/min: 5 mg PO qDay
Peritoneal dialysis: 5 mg PO qDay
Intermittent hemodialysis: 5 mg PO qDay; may also administer 3 times weekly
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity; lactation.
Precautions
Hepatic or renal impairment; elderly; tasks requiring mental alertness eg, driving or operating heavy machinery; pregnancy.
Lactation: Excreted in breast milk; use not recommended
Pregnancy-Lactation
Interactions
Additive CNS depression when administered concomitantly w/ other CNS depressants (e.g. sedatives, tranquilisers).
Adverse Effects
Side effects of Cetirizine :
>10%
Somnolence (2-14%),Headache (11-14%)
1-10%
Fatigue (5.9%),Dry mouth (5%),Dizziness (2%),Diarrhea (2-3%),Malaise (4%),Bronchospasm (2-3%),Vomiting (2-3%),Epistaxis (2-4%)
<1%
Stomach pain,Drowsiness,Angioedema,Fussiness,Hallucinations,Hypotension,Tremor,Tongue discoloration
Mechanism of Action
Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and resp tract.
Note
T Zine 10mg Tablet manufactured by Quest Pharmaceuticals Pvt. Ltd.. Its generic name is Cetirizine. T Zine is availble in Nepal.
Farmaco Nepal drug index information on T Zine Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.