Taenicid Tablet
Praziquantel
600mg
Deurali Janta Pharmaceuticals Pvt. Ltd.
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| Retail Price | 160.00 NPR |
Indications
Taenicid Tablet is used for:
Schistosomiasis, Intestinal fluke infections; Lung fluke infections; Clonorchiasis ; Opisthorchiasis, Tapeworm infections
Adult Dose
Oral
Schistosomiasis
Adult: 3 doses of 20 mg/kg every 4-6 hr or 40-60 mg/kg as a single dose.
Intestinal fluke infections; Lung fluke infections; Clonorchiasis ; Opisthorchiasis
Adult: 25 mg/kg tid for 1-2 days or 40 mg/kg as a single daily dose.
Tapeworm infections
Adult: 5-25 mg/kg as a single dose.
Neurocysticercosis
Adult: 50 mg/kg/day, given in 3 divided doses for 14 days. Alternatively, 3 doses of 25 mg/kg every 2 hr.
Child Dose
Oral
Schistosomiasis
Child: >4 yr: 3 doses of 20 mg/kg every 4-6 hr or 40-60 mg/kg as a single dose.
Intestinal fluke infections; Lung fluke infections; Clonorchiasis ; Opisthorchiasis
Child: >4 yr: 25 mg/kg tid for 1-2 days or 40 mg/kg as a single daily dose.
Tapeworm infections
Child: >4 yr: 5-25 mg/kg as a single dose.
Renal Dose
Administration
Should be taken with food. Swallow whole, do not chew/crush.
Contra Indications
Hypersensitivity, ocular cysticercosis.
Precautions
Driving or operating machinery during or for 24 hr after treatment. Severe hepatic disease. Do not breastfeed during or for 72 hr after treatment.
Lactation: enters breast milk, do not nurse on the day of taking drug & 72 hr thereafter
Pregnancy-Lactation
Interactions
Reduced plasma concentrations when used with dexamethasone. Carbamazepine, phenytoin and chloroquine may reduce the bioavailability of praziquantel while cimetidine may increase the bioavailabilty of praziquantel.
Adverse Effects
Side effects of Praziquantel :
1-10%
Appetite loss,Dizziness,Drowsiness,Headache,Malaise,CSF reaction syndrome in patients treated for neurocysticercosis,Abdominal pain,Nausea,Vomiting,Diaphoresis
<1%
Diarrhea,Fever,Itching,Rash,Urticaria
Mechanism of Action
Praziquantel is an anthelmintic with a broad spectrum of activity against trematodes (flukes) and cestodes (tapeworms). It increases the cell permeability to Ca in schistosomes, causing strong contractions and paralysis of worm musculature leading to detachment of suckers from the blood vessel walls and to dislodgement.
Note
Taenicid 600mg Tablet manufactured by Deurali Janta Pharmaceuticals Pvt. Ltd.. Its generic name is Praziquantel. Taenicid is availble in Nepal.
Farmaco Nepal drug index information on Taenicid Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.