Tiova Inhaler
Tiotropium
18mcg
Cipla Ltd.
| Pack size | 1's |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 554.25 NPR |
Available as:
Indications
Tiova Inhaler is used for:
Asthma, COPD
Adult Dose
Inhalation
Asthma; Chronic obstructive pulmonary disease
Adult: As Inhaler: 2 puffs (18mcg) once daily.
As inhalation cap: 1 cap (18 mcg) daily via inhaler device, at the same time each day.
Child Dose
Inhalation
Asthma
Child> 12 years: As Inhaler: 2 puffs (18mcg) once daily.
Child> 18 years: As inhalation cap: 1 cap (18 mcg) daily via inhaler device, at the same time each day.
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
<50 Use w/ caution.
Administration
Contra Indications
Hypersensitivity to atropine and its derivatives (e.g. ipratropium).
Precautions
Patient w/ narrow-angle glaucoma, prostatic hyperplasia/bladder neck obstruction, cystic fibrosis. History of MI (<6 mth), or unstable or life threatening cardiac arrhythmia w/in the past yr. Not intended for use as initial treatment for acute bronchospasm and as monotherapy for asthma. Moderate to severe renal impairment (CrCl ≤50 mL/min). Pregnancy and lactation. Patient Counselling This drug may cause dizziness and blurred vision, if affected, do not drive or operate machinery. Monitoring Parameters Monitor pulmonary function.
Pregnancy-Lactation
Interactions
Other anticholinergic agents.
Adverse Effects
Side effects of Tiotropium :
>10%
Upper respiratory tract infection (41%),Dry mouth (16%),Sinusitis (11%)
1-10%
Abdominal pain,Allergic reaction,Angina pectoris (including aggravated angina pectoris),Cataract,Chest pain (nonspecific),Constipation,Depression,Dyspepsia,Dysphonia,Edema,Epistaxis,Gastroesophageal reflux,Herpes zoster,Hypercholesterolemia,Hyperglycemia,Infection,Laryngitis,Leg pain,Moniliasis,Myalgia,Paresthesia,Pharyngitis,Rash,Rhinitis,Skeletal pain,Stomatitis (including ulcerative stomatitis),Urinary tract infection,Vomiting
<1%
Angioedema,Fibrillation,Supraventricular tachycardia,Urinary retention
Mechanism of Action
Tiotropium bromide, a long-acting quaternary ammonium antimuscarinic, is structurally related to ipratropium. It is a nonselective competitive antagonist of muscarinic (M1-M5) receptors and causes bronchodilation by inhibiting the actions of acetylcholine and other cholinergic stimuli at M3 receptors in the smooth muscle of the respiratory tract.
Note
Tiova 18mcg Inhaler manufactured by Cipla Ltd.. Its generic name is Tiotropium. Tiova is availble in Nepal.
Farmaco Nepal drug index information on Tiova Inhaler is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.