Tobacin D Eye Drop
Dexamethasone 0.1% + Tobramycin 0.3% Eye prep
0.1% + 0.3%
Aristo Pharmaceuticals Ltd.
| Pack size | 5ml |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 76.40 NPR |
Indications
Tobacin D Eye Drop is used for:
Bacterial eye infections, Ocular inflammation, Pink eye
Adult Dose
Ophthalmic
Ocular inflammation with suspected or confirmed bacterial infection
Adult: As Eye Drops: 1-2 drops instilled into the conjunctival sac(s) 4-6 hrly. Dosage may be increased to every 2 hrly during the initial 24-48 hr, decrease frequency gradually as improvement seen.
As Ointment: Apply about ½ inch of ointment into the conjunctival sac(s) up to 3-4 times daily.
Child Dose
Ophthalmic
Ocular inflammation with suspected or confirmed bacterial infection
<2 years
Safety and efficacy not established
>2 years
As Eye Drops: 1-2 drops instilled into the conjunctival sac(s) 4-6 hrly. Dosage may be increased to every 2 hrly during the initial 24-48 hr, decrease frequency gradually as improvement seen.
As Ointment: Apply about ½ inch of ointment into the conjunctival sac(s) up to 3-4 times daily.
Renal Dose
Administration
Contra Indications
Viral infections of corneal and conjunctiva (e.g. epithelial herpes simplex keratitis, vaccinia, varicella). Mycobacterial or fungal infection of the eye.
Precautions
Pregnancy and lactation. Avoid prolonged use, monitor intraocular pressure routinely. Safety and effectiveness in children <2 yr not established.
Lactation: Excretion in milk unknown; use with caution
Pregnancy-Lactation
Interactions
Antagonistic effect w/ neostigmine and pyridostigmine. May potentiate the effect of warfarin and phenindione.
Adverse Effects
Side effects of Dexamethasone 0.1% + Tobramycin 0.3% Eye prep :
Hypersensitivity reactions, lid itching and swelling, conjunctival erythema, increase in intraocular pressure, glaucoma, optic nerve damage, posterior subcapsular cataract formation and delayed wound healing. Secondary infections especially after prolonged use.
Mechanism of Action
Tobramycin, an aminoglycoside antibiotic, has actions similar to that of gentamicin and is active against Staphylococci, Streptococci, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, most Proteus vulgaris strains, Haemophilus influenzae and H. aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus and some Neisseria species.
Dexamethasone, a synthetic fluorinated corticosteroid, has mainly glucocorticoid activity and suppresses inflammatory response.
Note
Tobacin D 0.1% + 0.3% Eye Drop manufactured by Aristo Pharmaceuticals Ltd.. Its generic name is Dexamethasone 0.1% + Tobramycin 0.3% Eye prep. Tobacin D is availble in Nepal.
Farmaco Nepal drug index information on Tobacin D Eye Drop is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.