Topalene Gel
Adapalene 0.1% Topical
0.1%
Maruti Pharma Pvt. Ltd.
| Pack size | 15g |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 130.00 NPR |
Indications
Topalene Gel is used for:
Acne, Keratosis pilaris
Adult Dose
Adult: Topical As 0.1% soln/cream/gel: Apply once daily at night after cleansing.
Child Dose
Renal Dose
Administration
Apply small (pea-sized) amount sparingly to entire face after cleansing with nonmedicated cleanser.
For topical use only;
Contra Indications
Hypersensitivity.
Precautions
Patients with sunburn, eczema. Pregnancy, lactation. Avoid excessive exposure to sunlight or UV irradiation. Keep away from the eyes, lips, nostrils and mucous membranes. Do not apply to cuts, abrasions, scaly or flaky skin, or patches of sunburned skin. Use with caution with preparations containing sulfur, resorcinol, or salicylic acid.
Lactation: Excretion in milk unknown; use with caution.
Pregnancy-Lactation
Interactions
Increased irritation may occur with medicated or abrasive soaps, products with a pronounced drying effect and those containing alcohol or astringents.
Adverse Effects
Side effects of Adapalene 0.1% Topical :
>10%
Dryness (1-45%),Scaling (1-44%),Burning/stinging (4-29%),Erythema (0.5-26%)
1-10%
Skin discomfort (6%),Pruritus (2%),Desquamation (2%),Sunburn (1%)
<1%
Acne flare,Conjunctivitis,Contact dermatitis,Eczema,Erythema,Eyelid edema,Rash,Skin discoloration
Mechanism of Action
Adapalene binds to specific retinoic acid nuclear receptors which normalises the differentiation of follicular epithelial cells resulting in decreased microcomedone formation.
Note
Topalene 0.1% Gel manufactured by Maruti Pharma Pvt. Ltd.. Its generic name is Adapalene 0.1% Topical. Topalene is availble in Nepal.
Farmaco Nepal drug index information on Topalene Gel is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.