Translipo Triple Cream
Gentamicin + Clotrimazole + Beclomethasone Topical
0.1% + 1% + 0.025%
Centaur Pharmaceuticals Pvt. Ltd.
| Pack size | 10gm |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 59.54 NPR |
Indications
Translipo Triple Cream is used for:
Dermatoses where secondary bacterial and/or candidal infection present.
Impetigo, Furunculosis, Secondary infected dermatoses, Napkin rashes, Otitis externa, Intertringinous eruptions, Atopic and discoid eczema, dermatitis, psoriasis, lichen simplex, discoid lupus erythematosus.
Adult Dose
Topical
As Cream/Ointment
Sufficient quantity should be applied bid-tid to cover completely affected skin area.
Child Dose
Safety & Efficacy not established.
Renal Dose
Administration
Contra Indications
Hypersensitivity to any of the ingredients.
Rosacea, acne, peri-oral dermatitis, tuberculosis of the skin and varicose ulcers. Skin lesions caused by infections with viruses (e.g. herpes simplex, vaccinia or varicella), fungi (e.g. candida, tinea) or bacteria (e.g. impetigo).
Precautions
For external use only. Do not use in or around the eye.
Not recommended during pregnancy & breast feeding.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Gentamicin + Clotrimazole + Beclomethasone Topical :
Prolonged and intensive treatment may cause local atrophic changes in the skin such as stria, thinning, loss of elasticity, dilatation of the superficial blood vessels, telangiectasia and ecchymosis.
Prolonged use, use of large amounts, treatment of extensive areas, or application to damaged skin, when is used and when the occlusive dressing technique is applied can result in sufficient systemic absorption to produce the features of hypercortisonism such as depression of the hypothalamic-pituitaryadrenal axis with consequent suppression of the adrenal gland. These effects are most likely to be severe in infants and children. Growth may be retarded and a Cushingoid state may be produced.
Benign intracranial hypertension has been reported less frequently. In infants the napkin may act as an occlusive dressing, and hence these preparations should not be used in the
nappy area for flexural eruptions. Ideally they should not be used in infants and young children at all.
Mechanism of Action
Beclomethasone controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes and fibroblasts, and reverses capillary permeability and lysosomal stabilization at the cellular level to prevent or control inflammation.
Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.
Gentamicin binds to 30s and 50s ribosomal subunits of susceptible bacteria disrupting protein synthesis, thus rendering the bacterial cell membrane defective.
Note
Translipo Triple 0.1% + 1% + 0.025% Cream manufactured by Centaur Pharmaceuticals Pvt. Ltd.. Its generic name is Gentamicin + Clotrimazole + Beclomethasone Topical. Translipo Triple is availble in Nepal.
Farmaco Nepal drug index information on Translipo Triple Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.