Trimovax (MMR) Injection
Measles and Rubella Vaccine (Live, attenuated)
Sanofi India Ltd.
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Indications
Trimovax (MMR) Injection is used for:
Measles, Rubella.
Adult Dose
Adults and Children: A single dose of 0.5 ml of the reconstituted vaccine given by deep subcutaneous injection.
EPI schedule: After completion of 9 months, 1 dose of measles-rubella vaccine should be given. After completion of 15 months, 1 dose of only measles containing vaccine should
be given.
Child Dose
Renal Dose
Administration
Contra Indications
Allergic to any ingredient in the vaccine.
Suffering from acute diseases, severe chronic diseases, acute exacerbation of chronic diseases and fever.
Pregnant women.
Immune deficiency, immune dysfunction or receiving immunosuppressive therapy.
Suffering from encephalopathy, uncontrolled epilepsy and other progressive neurological diseases.
Precautions
Family and personal history of seizures, suffering from chronic diseases, with history of epilepsy, allergic constitution, breastfeeding women.
The people receiving vaccination should be observed at the site for at least 30 minutes after injection.
The people receiving injection of immune globulin should be vaccinated with an intervalof at least 3 months so as not to affect the immune effect.
Other attenuated live vaccine should be vaccinated with an interval of at least 1 month from this vaccine, but this vaccine can be vaccinated simultaneously with attenuated
live mumps vaccine.
This product is an attenuated live vaccine and it is not recommended to be used in the epidemic season.
Women of childbearing age should avoid pregnancy within at least 3 months after injection of this vaccine.
Pregnancy-Lactation
Interactions
Affected by Ig.
Adverse Effects
Side effects of Measles and Rubella Vaccine (Live, attenuated) :
Common side-effects :
Generally pain and tenderness at the injection site may occur within 24 hours after vaccination, which usually disappear by itself within 2-3 days.
Generally transient fever reaction may occur within 1-2 weeks after vaccination.
Rash: generally mild rash may occur within 12 days after vaccination, which generally lasts for no more than 2 days.
Rare side- effects:
Severe fever reaction: physical methods and drugs should be used for symptomatic treatment to prevent febrile seizures.
Very rare side-effects:
Allergic rash: generally urticaria may occur within 72 hours after vaccination, and if this reaction occurs, anti-allergy treatment should be timely given.
Anaphylactic shock: generally occurs within 1 hour after vaccination. Injection of epinephrine and other emergency measures should be timely given for treatment.
Anaphylactoid purpura: medical care should be timely given if anaphylactoid purpura occurs. Cortical steroids can be given for anti-allergy treatment. Improper or not timely treatment is likely to cause anaphylatic purpura nephritis.
Thrombocytopenia purpura.
Adults may develop arthritis, pain and swelling of large joints after vaccination
Mechanism of Action
Live, attenuated viruses stimulate active immunity to disease caused by measles and rubella viruses.
Note
Trimovax (MMR) Injection manufactured by Sanofi India Ltd.. Its generic name is Measles and Rubella Vaccine (Live, attenuated). Trimovax (MMR) is availble in Nepal.
Farmaco Nepal drug index information on Trimovax (MMR) Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.