Tropan XL 5 Tablet

Oxybutynin Hydrochloride
5mg
Sun Pharmaceutical Industries Ltd.
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Indications

Tropan XL 5 Tablet is used for: Overactive bladder

Adult Dose

Oral Overactive bladder Adult: As extended-release preparation: Initially, 5 mg once daily increased by 5 mg every wk if necessary to max 30 mg daily.

Child Dose

Oral Detrusor Overactivity, Nocturnal enuresis Bladder overactivity associated with a neurologic condition (eg, spina bifida) Child >6 years (extended-release): 5 mg/day PO initially; may be increased by 5 mg/day at weekly intervals; not to exceed 20 mg/day

Renal Dose

Administration

May be taken with or without food.

Contra Indications

GI obstruction or atrophy, severe toxic megacolon, significant bladder outflow obstruction, glaucoma, urinary retention.

Precautions

Elderly; hepatic or renal impairment; neuropathy; hyperthyroidism; prostatic hyperplasia; hiatus hernia; cardiac disease, reflux oesophagitis, ulcerative colitis, myasthenia gravis; pregnancy and lactation. High environmental temperature might cause heat prostration (fever with heat stroke due to decreased sweating). Lactation: Unknown; use with caution

Pregnancy-Lactation

Interactions

Co-administration with other anticholinergic drugs may cause undesirable increased anticholinergic effects. Additive sedation with CNS depressants and alcohol. Concentration may be increased by CYP3A4 inhibitirs (e.g. imidazole antifungals, macrolide antibiotics).

Adverse Effects

Side effects of Oxybutynin Hydrochloride : >10% Dry mouth (21-71%),Constipation (7-15%),Somnolence (2-14%),Nausea (2-12%) 1-10% Asthenia (6-10%),Dizziness (6-10%),Headache (6-10%),Blurred vision (6-10%),Dry eyes (6-10%),Diarrhea (6-10%),Nausea (6-10%),Pain (6-10%),Rhinitis (6-10%) <1% Anorexia,Fluid retention,Hot flush,Dysphonia,Dysphagia,Frequent bowel movements,Chest discomfort,Thirst Frequency Not Defined Cycloplegia,Impairment of mental alertness,Memory impairment,Mydriasis,Tachycardia,QT prolongation

Mechanism of Action

Oxybutynin exerts direct antispasmodic effect on the smooth muscle by inhibiting the muscarinic action of acetylcholine. It exhibits moderate anticholinergic effect, but has potent antispasmodic effects on urinary smooth muscle.

Note

Tropan XL 5 5mg Tablet manufactured by Sun Pharmaceutical Industries Ltd.. Its generic name is Oxybutynin Hydrochloride. Tropan XL 5 is availble in Nepal. Farmaco Nepal drug index information on Tropan XL 5 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Oxybutynin Hydrochloride :