Ultrasol SA Ointment
Halobetasol + Salicyclic Acid Topical
Deurali Janta Pharmaceuticals Pvt. Ltd.
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| Retail Price | 240.00 NPR |
Indications
Ultrasol SA Ointment is used for:
For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Adult Dose
Inflammatory, Pruritic & Steroid-Responsive Dermatoses
Apply topically to affected area(s) BID-TID
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity to any of the components. Topical hydrocortisone is contraindicated in viral, tuberculosis and fungal skin infections.
Precautions
Long term continuous therapy should be avoided, particularly in the face, on flexures, and intertrigenous areas, and in infants and children
Systemic absorption of topical corticosteroids may cause reversible hypothalamic-pituitaryadrenal (HPA) axis suppression, manifestations of cushing\'s syndrome, hyperglycemia, and glucosuria. Patients receiving large dose of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid.
Lactation: excretion of topical corticosteroids in breast milk is unknown; use with caution
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Halobetasol + Salicyclic Acid Topical :
Stinging/burning of skin, Desquamation. As with other topical steroids, prolonged and intensive treatment may cause local atrophic changes of the skin, such as striae, thinning and dilatation of the superficial blood vessels, particularly when occlusive dressing is used or when skin folds are involved. Systemic absorption, sufficient to produce adrenal suppression, can occur with prolonged or extensive use, specially when napkin is used. Infants and children are particularly at risk. Caution should be exercised if a topical steroid is used near the eye. Glaucoma might be the result if the preparation enters the eye.
Mechanism of Action
Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing release of destructive acid hydrolases from leukocytes; inhibiting macrophage accumulation in inflamed areas; reducing leukocyte adhesion to capillary endothelium; reducing capillary wall permeability and edema formation; decreasing complement components; antagonizing histamine activity and release of kinin from substrates; reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation.
Salicylic acid has a potent keratolytic action and a slight antiseptic action when applied topically. It softens and destroys the stratum corneum by increasing endogenous hydration which causes the horny layer of the skin to swell, soften, and then desquamate. At high concentrations, salicylic acid has a caustic effect. It also possesses weak antifungal and antibacterial activity.
Note
Ultrasol SA Ointment manufactured by Deurali Janta Pharmaceuticals Pvt. Ltd.. Its generic name is Halobetasol + Salicyclic Acid Topical. Ultrasol SA is availble in Nepal.
Farmaco Nepal drug index information on Ultrasol SA Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.