Vermisol Tablet
Levamisole
150mg
Khandelwal Laboratories Pvt Ltd
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Indications
Vermisol Tablet is used for:
Ascariasis, Ancylostomiasis
Adult Dose
Oral
Ascariasis
Adult: 150 mg as a single dose.
Mixed ascariasis-hookworm infections; Ancylostomiasis
Adult: 2.5 mg/kg as a single dose, repeated after 7 days in severe cases.
Child Dose
Oral
Ascariasis
Child: 3 mg/kg as a single dose.
Mixed ascariasis-hookworm infections; Ancylostomiasis
Child: 2.5 mg/kg as a single dose, repeated after 7 days in severe cases.
Renal Dose
Administration
Should be taken with food. Take w/ meals to minimise side effects eg nausea.
Contra Indications
Preexisting blood disorders; pregnancy and lactation; rheumatoid arthritis; severe renal impairment.
Precautions
Hepatic impairment, Sjogren's syndrome.
Pregnancy-Lactation
Interactions
May increase toxicity of phenytoin. Increases bioavailability of ivermectin; decreases bioavailability of albendazole. Alcohol causes disulfiram-like reaction.
Adverse Effects
Side effects of Levamisole :
Nausea, vomiting, diarrhoea, abdominal pain, dizziness and headache. Fever, influenza-like syndrome, arthralgia, muscle pain, rash, taste disturbances and cutaneous vasculitis.
Potentially Fatal: Agranulocytosis, leucopenia, thrombocytopenia.
Mechanism of Action
Levamisole is the active laevo-isomer of tetramisole. It works by paralysing susceptible intestinal worms which are then excreted from the intestines. Levamisole also enhances cellular immune responses in humans.
Note
Vermisol 150mg Tablet manufactured by Khandelwal Laboratories Pvt Ltd. Its generic name is Levamisole. Vermisol is availble in Nepal.
Farmaco Nepal drug index information on Vermisol Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.