Welcox Capsule
Ampicillin + Cloxacillin
250mg + 250mg
Everest Pharmaceuticals Pvt. Ltd.
| Pack size | |
|---|---|
| Dispensing mode | |
| Source | |
| Agent | |
| Retail Price | 8.48 NPR |
Indications
Welcox Capsule is used for:
Susceptible infections
Adult Dose
Oral
Susceptible infections
Adult: Per capsule contains ampicillin 250 mg and cloxacillin 250 mg: 1 capsule 4 times daily. In severe infections, the dose can be increased up to 12 capsules daily.
Child Dose
Oral
Susceptible infections
Child: Per 5ml contains ampicillin 125 mg and cloxacillin 125 mg: 1 tsf 4 times daily.
Renal Dose
Administration
Contra Indications
Penicillin allergy.
Precautions
Allergy to cephalosporins, infectious mononucleosis, neonates with jaundice, history of convulsions, lactation.
Pregnancy-Lactation
Interactions
Failure of oral contraceptives, increased rash with allopurinol, reduced bactericidal activity with chloramphenicol, erythromycin and tetracyclines.
Adverse Effects
Side effects of Ampicillin + Cloxacillin :
G.I.disturbances, pruritus, urticaria, erythema, exfoliative dermatitis, rashes, fever, joint pain, eosinophilia, bronchial asthma, angioneuratic oedema, hemolytic anaemia, serum sickness, CNS effects like hyperactivity, agitation, insomnia, anxiety, behavioural changes, confusion, dizziness and convulsions.
Potentially Fatal: Anaphylactic reaction.
Mechanism of Action
Ampicillin exerts bactericidal action on both gm+ve and gm-ve organisms. Its spectrum includes gm+ve organisms eg, S pneumoniae and other Streptococci, L monocytogenes and gm-ve bacteria eg, M catarrhalis, N gonorrhoea, N meningitidis, E coli, P mirabilis, Salmonella, Shigella, and H influenzae. Ampicillin exerts its action by inhibiting the synthesis of bacterial cell wall.
Cloxacillin is a penicillinase-resistant penicillin. It is active against gm+ve organisms including penicillinase-producing strains of Staphylococci. Cloxacillin is highly active against Staph aureus, Strep pyogenes, Strep viridans and Strep pneumoniae. It is also active against penicillinase-producing gonococci and against N meningitidis and H influenzae. Other gm-ve organisms are resistant to cloxacillin as are also methicillin-resistant strains of Staphylococci.
Note
Welcox 250mg + 250mg Capsule manufactured by Everest Pharmaceuticals Pvt. Ltd.. Its generic name is Ampicillin + Cloxacillin. Welcox is availble in Nepal.
Farmaco Nepal drug index information on Welcox Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
Some other brands of Ampicillin + Cloxacillin :
Capsule
Stylox
250mg + 250mg
Nepal Pharmaceuticals Pvt. Ltd.
Capsule
Stylox DT
125mg + 125mg
Nepal Pharmaceuticals Pvt. Ltd.
Capsule
Periclox
250mg + 250mg
Deurali Janta Pharmaceuticals Pvt. Ltd.
Suspention
Periclox
125mg + 125mg/5ml
Deurali Janta Pharmaceuticals Pvt. Ltd.
Suspention
Stylox
Nepal Pharmaceuticals Pvt. Ltd.