Benzoyl Peroxide topical
Indications
Benzoyl Peroxide topical is used for:
Acne vulgaris, Dyeing hair, Teeth whitening, Decubitus or Stasis ulcers
Adult Dose
Topical/Cutaneous
Acne
Adult: As 2.5-10% preparation: Apply 1-2 times daily after cleansing, may gradually increase to tid if needed. Start w/ lower strength preparations.
As cleanser: Wash 1-2 times daily.
Child Dose
Renal Dose
Administration
Apply sparingly to affected areas after thoroughly washing skin;
Contra Indications
Hypersensitivity.
Precautions
Discontinue if severe irritation develops. Restart with tolerable levels of treatment after irritiation has cleared. Do not use occlusive dressing. May cause dermatitis in allergic patients. Apply carefully near the eyes, mouth, neck and other mucous membranes as well as other sensitive areas.
Lactation: excretion in milk unknown; use with caution
Pregnancy-Lactation
Interactions
PABA sunscreens may transiently discolour fabric.
Adverse Effects
Side effects of Benzoyl Peroxide topical :
Excessive drying of skin, allergic dermatitis. May bleach fabrics or hair. Skin discoloration; skin rash, peeling, transient local oedema.
Mechanism of Action
Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its oxidative property. It is active against S.epidermidis and P.acne.