Benzoyl Peroxide topical

Indications

Benzoyl Peroxide topical is used for: Acne vulgaris, Dyeing hair, Teeth whitening, Decubitus or Stasis ulcers

Adult Dose

Topical/Cutaneous Acne Adult: As 2.5-10% preparation: Apply 1-2 times daily after cleansing, may gradually increase to tid if needed. Start w/ lower strength preparations. As cleanser: Wash 1-2 times daily.

Child Dose

Renal Dose

Administration

Apply sparingly to affected areas after thoroughly washing skin;

Contra Indications

Hypersensitivity.

Precautions

Discontinue if severe irritation develops. Restart with tolerable levels of treatment after irritiation has cleared. Do not use occlusive dressing. May cause dermatitis in allergic patients. Apply carefully near the eyes, mouth, neck and other mucous membranes as well as other sensitive areas. Lactation: excretion in milk unknown; use with caution

Pregnancy-Lactation

Interactions

PABA sunscreens may transiently discolour fabric.

Adverse Effects

Side effects of Benzoyl Peroxide topical : Excessive drying of skin, allergic dermatitis. May bleach fabrics or hair. Skin discoloration; skin rash, peeling, transient local oedema.

Mechanism of Action

Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its oxidative property. It is active against S.epidermidis and P.acne.