Besifloxacin 0.6% Eye prep

Indications

Besifloxacin 0.6% Eye prep is used for: Bacterial Conjunctivitis

Adult Dose

Adults: Instill one drop in the affected eye(s) 3 times a day for 7 days.

Child Dose

Children (1 year of age and older): Instill one drop in the affected eye(s) 3 times a day for 7 days.

Renal Dose

Administration

Contra Indications

This drug is contraindicated in patients with a history of hypersensitivity to Besifloxacin, to other Quinolones or to any of the components in this formulation.

Precautions

• This drug is for topical ophthalmic use only and should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye. • As with other anti-infectives, prolonged use may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, discontinue use and institute alternative therapy. • To prevent contamination do not touch the tip of the dropper to eye, eyelid or any surface of the affected eye. • Patients should not wear contact lenses during the course of therapy with this drug. • Shake well before use. Lactation: Excretion in milk unknown; use caution

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Besifloxacin 0.6% Eye prep : 1-10% Blurred vision,Conjunctival redness,Eye irritation,Eye pain,Eye pruritus,Headache

Mechanism of Action

Bactericidal Inhibits DNA-gyrase (a topoisomerase) in susceptible organisms, which in turn inhibits cell division.